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[ACUTE VISION LOSS ASSOCIATED WITH HYPEREOSINOPHILIC SYNDROME]. | LitMetric

[ACUTE VISION LOSS ASSOCIATED WITH HYPEREOSINOPHILIC SYNDROME].

Harefuah

Department of Ophthalmology, Bnai Zion Medical Center, Haifa, Israel.

Published: October 2022

AI Article Synopsis

  • Hypereosinophilic syndrome (HES) is a rare condition characterized by high eosinophil levels that can damage various tissues, leading to serious complications like stroke in 12% of patients.
  • The main treatment goal is to lower eosinophil counts and reduce their duration in tissues, often supported by the use of anticoagulants.
  • A reported case illustrates that timely diagnosis and proper treatment can significantly minimize tissue damage and preserve functionality in patients suffering from HES.

Article Abstract

Hypereosinophilic syndrome (HES) is a rare disorder, in which eosinophilic toxins damage capillary and coronary endothelium and neuronal axons, at different target organs; 12% of patients experience stroke as a result of endothelial dysfunction, cardiomyopathy with secondary embolism, hyperviscosity and hypercoagulability. The treatment target is to lower the eosinophil count and shorten its tissue survival time. Supportive care and anticoagulants are given as required. We report a case of myocarditis, respiratory failure and cortical blindness due to rapidly deteriorating HES. The case demonstrates how early recognition and appropriate treatment can reduce tissue toxicity and functional loss due to hypereosinophilic syndrome.

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