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| http://dx.doi.org/10.1111/pbi.13953 | DOI Listing |
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Methylome profiling of cell-free DNA during the early life course in (un)complicated pregnancies using MeD-seq: Protocol for a cohort study embedded in the prospective Rotterdam periconception cohort.
PLoS One
January 2025
Department of Obstetrics and Gynaecology, Erasmus Medical Centre Rotterdam, Rotterdam, The Netherlands.
Introduction: Placental DNA methylation differences have been associated with timing in gestation and pregnancy complications. Maternal cell-free DNA (cfDNA) partly originates from the placenta and could enable the minimally invasive study of placental DNA methylation dynamics. We will for the first time longitudinally investigate cfDNA methylation during pregnancy by using Methylated DNA Sequencing (MeD-seq), which is compatible with low cfDNA levels and has an extensive genome-wide coverage.
View Article and Find Full Text PDFSARS-CoV-2-induced cytokine storm drives prolonged testicular injury and functional impairment in mice that are mitigated by dexamethasone.
PLoS Pathog
January 2025
Department of Tropical Medicine, Medical Microbiology and Pharmacology, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, Hawaii, United States of America.
Compromised male reproductive health, including reduced testosterone and sperm count, is one of the long COVID symptoms in individuals recovering from mild-severe disease. COVID-19 patients display testicular injury in the acute stage and altered serum fertility markers in the recovery phase, however, long-term implications on the testis remain unknown. This study characterized the consequences of SARS-CoV-2 on testis function.
View Article and Find Full Text PDFThe proteomic content of Varroa destructor gut varies according to the developmental stage of its host.
PLoS Pathog
December 2024
Centre de Recherche sur la Biodiversité et l'Environnement (CRBE), UMR5174, CNRS-Université de Toulouse III-IRD, Université Paul Sabatier, Toulouse, France.
The nutritional physiology of parasites is often overlooked although it is at the basis of host-parasite interactions. In the case of Varroa destructor, one of the major pests of the Western honey bee Apis mellifera, the nature of molecules and tissues ingested by the parasite is still not completely understood. Here, the V.
View Article and Find Full Text PDFGrowth Superiority and Genetic Characterization of the Hybrid from Female Ussuri Catfish () and Male Longsnout Catfish ().
Animals (Basel)
December 2024
State Key Laboratory of Freshwater Ecology and Biotechnology, Hubei Hongshan Laboratory, The Innovation Academy of Seed Design, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, China.
Crossbreeding is a traditional breeding technique and has been performed successfully in many fish species. However, distant hybridization between different genera is hard to be successful because of reproductive isolation. In this study, diploid hybrids (PL) were successfully derived from the hybridization of Ussuri catfish (, PU, ♀, 2n = 52) and longsnout catfish (, LL, ♂, 2n = 52).
View Article and Find Full Text PDF[Polycystic Ovary Syndrome and Mental Health in Adolescents].
Andes Pediatr
October 2024
Facultad de Medicina Occidente, Universidad de Chile, Santiago, Chile.
Article Synopsis
- Polycystic Ovary Syndrome (PCOS) is the most common endocrine disorder in female adolescents, leading to various health issues, including metabolic and psychiatric problems.
- Recent studies indicate a higher risk of mental health disorders like anxiety, depression, and eating disorders in women with PCOS, and potential neurodevelopmental risks for their children as well.
- The underlying causes for these mental health associations are not fully understood yet, emphasizing the need for better mental health assessments and collaboration among healthcare providers in managing PCOS.
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