The publication of Resource articles is essential for the dissemination of novel, or substantially enhanced, tools, techniques, disease models, datasets and resources. By sharing knowledge and resources in a globally accessible manner, we can support human disease research to accelerate the translation of fundamental discoveries to effective treatments or diagnostics for diverse patient populations. To promote and encourage excellence in Resource articles, Disease Models & Mechanisms (DMM) is launching a new 'Outstanding Resource Paper Prize'. To celebrate this, we highlight recent outstanding DMM Resource articles that have the ultimate goal of benefitting of human health.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10655811 | PMC |
http://dx.doi.org/10.1242/dmm.049944 | DOI Listing |
ACS Nano
January 2025
State Key Laboratory of Pollution Control and Resource Reuse, School of Environment, Nanjing University, Nanjing 210023, China.
Under a changing climate, enhancing the drought resilience of crops is critical to maintaining agricultural production and reducing food insecurity. Here, we demonstrate that seed priming with amorphous silica (SiO) nanoparticles (NPs) (20 mg/L) accelerated seed germination speed, increased seedlings vigor, and promoted seedling growth of rice under polyethylene glycol (PEG)-mimicking drought conditions. An orthogonal approach was used to uncover the mechanisms of accelerated seed germination and enhanced drought tolerance, including electron paramagnetic resonance, Fourier transform infrared spectroscopy (FTIR), metabolomics, and transcriptomics.
View Article and Find Full Text PDFACS Appl Mater Interfaces
January 2025
School of Materials and Energy, Lanzhou University, Lanzhou 730000, China.
Copper-tantalum (Cu-Ta) immiscible alloy nanoparticles (NPs) have been the subject of extensive research in the field of structural materials, due to their exceptional nanostructural stability and high-temperature creep properties. However, Cu is also a highly active oxidation catalyst due to its abundant valence changes. In this study, we have for the first time obtained homogeneous CuTa ( = 0.
View Article and Find Full Text PDFACS Appl Mater Interfaces
January 2025
School of Food Science and Engineering, South China University of Technology, Guangzhou 510641, China.
The involvement of neurons in the peripheral nervous system is crucial for bone regeneration. Mimicking extracellular matrix cues provides a more direct and effective strategy to regulate neuronal activity and enhance bone regeneration. However, the simultaneous coupling of the intrinsic mechanical-electrical microenvironment of implants to regulate innervated bone regeneration has been largely neglected.
View Article and Find Full Text PDFJACC Clin Electrophysiol
December 2024
The Hull Family Cardiac Fibrillation Management Laboratory, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada.
Background: Conduction velocity (CV) is a measure of the health of myocardial tissue. It can be measured by taking differences in local activation times from intracardiac electrodes. Several factors introduce error into the measurement, among which ignoring the 3-dimensional aspect is a major detriment.
View Article and Find Full Text PDFJ Perianesth Nurs
January 2025
Division of Abdominal Transplantation, Carolinas Medical Center, Wake Forest University School of Medicine, Atrium Health, Charlotte, NC.
Purpose: Understanding barriers to compliance can aid in mitigation strategies to address them. This study aims to quantitatively and qualitatively assess the relationship between barriers to ERAS recommendations and perceived ability to assure compliance among multidisciplinary team (MDT) members who deliver Enhanced Recovery After Surgery (ERAS) care.
Design: Embedded mixed-methods survey analysis.
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