[Research progress of resorption of lumbar disc herniation].

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi

Department of Orthopaedics, the Affiliated Hospital of Kunming University of Science and Technology, the First People's Hospital of Yunnan Province, Kunming Yunnan, 650034, P. R. China.

Published: October 2022

Objective: To summarize the research progress of resorption of lumbar disc herniation (RLDH).

Methods: The literature on RLDH at home and abroad in recent years was reviewed to summarize its influencing factors, pathogenesis, imaging findings, and predictive effect, as well as its influence on the treatment selection of lumbar disc herniation (LDH).

Results: The main mechanism of RLDH is the combined effect of inflammatory response and neovascularization. Age, smoking, body mass index, and clinical manifestations are the influencing factors. Studies have shown that the annular enhancement around the nucleus pulposus on enhanced MRI images is the characteristic imaging manifestation of RLDH, which is a predictor of whether RLDH occurs. In the treatment of LDH, cyclooxygenase 2 inhibitors may have a negative impact on RLDH.

Conclusion: The occurrence of RLDH suggests that strict conservative treatment is the first choice for LDH treatment, but surgery is still an important treatment method when the patient's symptoms and imaging symptoms don't significantly improved after conservative treatment.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9626275PMC
http://dx.doi.org/10.7507/1002-1892.202204105DOI Listing

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