Objective: Determine if the ideal location of the construct in microtia reconstruction for hemifacial microsomia (HFM) can be more accurately derived from measurements on the cranium.
Design: High-resolution computerized tomography (CT) images were analyzed through craniometric linear relationships.
Setting: Our tertiary care institution from 2000 to 2021.
Patients/participants: Patients diagnosed with HFM and microtia, who had high-resolution craniofacial CT scans, yielding 36 patients accounting for 44 CT scans.
Main Outcome Measure(s): First, the integrity of the posterior cranial vault among HFM patients was determined. If proven to be unaffected, it could be used as a reference in the placement of the construct. Second, the position of the ear in relation to the cranium was assessed in healthy age-matched controls. Third, if proven to be useful, the concordance of these cranium-based relationships could be validated among our HFM cohort.
Results: The posterior cranial vault is unaffected in HFM ( > .001). Further, craniometric relationships between the tragus and the Foramen Magnum, as well as between the tragus and the posterior cranium, have been shown to be highly similar and equally precise in predicting tragus position in healthy controls ( > .001). These relationships held true across all age groups ( > .001), and importantly among HFM patients, where the mean absolute difference in predicted tragus position never surpassed 1.5 mm.
Conclusions: Relationships between the tragus and the cranium may be used as an alternative to distorted facial anatomy or surgeon's experience to assist in pre-operative planning of construct placement in microtia reconstruction for HFM patients.
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http://dx.doi.org/10.1177/10556656221135925 | DOI Listing |
J Craniofac Surg
November 2024
Department of Auricular Reconstruction, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College.
Cases of microtia combined with pulmonary hypoplasia are occasionally in clinics, and its genetic etiology has so far proved inconclusive. Here, aiming to contribute to a better understanding of microtia-related comorbid respiratory anomalies, the authors provide a clinical and genetic description of a rare trio family of which the son suffers combined deformities of right microtia, left pulmonary hypoplasia, and dextrocardia using whole-genome sequence (WGS). A novel potential pathologic compound heterozygosity in the FREM1 gene was identified and validated by the trio and bioinformatics analysis.
View Article and Find Full Text PDFBiomater Adv
January 2025
Department of Chemistry, Materials and Chemical Engineering G. Natta, Politecnico di Milano, Piazza Leonardo Da Vinci 32, Milan, Italy; Local Unit Politecnico di Milano, Milan, Italy. Electronic address:
Microtia, along with trauma, represents one of the main causes of external ear malformation. Different clinical techniques were developed for the reconstruction of the auricle, but they all have some drawbacks. This work is focused on the development of an innovative 3D porous scaffold, printed by Fused Deposition Modelling (FDM) and based on laser-scanned images of the healthy contralateral ear of the patient.
View Article and Find Full Text PDFJ Craniofac Surg
January 2025
Plastic Surgery Hospital and Institute, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Background: Postoperative infection is one of the main complications that affect the surgical effect of auricular reconstruction with tissue expansion. Understanding the susceptible time and distribution of pathogens is especially important for the treatment.
Method: The data of patients with infection after auricular reconstruction with tissue expansion from September 1, 2018 to August 30, 2024 were collected retrospectively.
Cleft Palate Craniofac J
January 2025
San Diego State University/UC San Diego Joint Doctoral Program in Clinical Psychology, San Diego, CA, USA.
Objective: Craniofacial conditions (CFCs) can be associated with adverse effects on quality of life (QoL). However, few studies have examined perceived benefits related to CFCs. This study described perceived benefits in an international sample of children and adolescents with CFCs and their parents.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Microtia is a congenital malformation characterized by underdevelopment of the external ear. While chondrocyte dysfunction has been implicated in microtia, the specific cellular abnormalities remain poorly understood. This study aimed to investigate mitochondrial dysfunction in microtia chondrocytes using single-cell RNA sequencing.
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