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| http://dx.doi.org/10.1111/srt.13226 | DOI Listing |
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Left Ventrolateral Prefrontal Cortical Activity During Reward Expectancy and Mania Risk.
JAMA Psychiatry
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Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania.
Importance: Mania/hypomania is the pathognomonic feature of bipolar disorder (BD). As BD is often misdiagnosed as major depressive disorder (MDD), replicable neural markers of mania/hypomania risk are needed for earlier BD diagnosis and pathophysiological treatment development.
Objective: To replicate the previously reported positive association between left ventrolateral prefrontal cortex (vlPFC) activity during reward expectancy (RE) and mania/hypomania risk, to explore the effect of MDD history on this association, and to compare RE-related left vlPFC activity in individuals with and at risk of BD.
Identification and Analysis of Amino Acid Metabolism-Related Subtypes in Lung Adenocarcinoma.
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Department of Thoracic Surgery, Guangxi Academy of Medical Sciences and the People's Hospital of Guangxi Zhuang Autonomous Region.
We aimed to explore the role of Amino acid metabolism (AAM) and identify biomarkers for prognosis management and treatment of lung adenocarcinoma. Differentially expressed genes (DEGs) associated with AAM in lung adenocarcinoma were selected from public databases. Samples were clustered into varying subtypes using ConsensusClusterPlus based on gene levels.
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Center for OCD and Related Disorders, Massachusetts General Hospital, Boston.
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Emory University Rollins School of Public Health, Department of Behavioral, Social, and Health Education Sciences.
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