AI Article Synopsis
- The study focuses on understanding the impact of SARS-CoV-2 and its variants on pediatric patients, aiming to identify key laboratory parameters for effective treatment.
- 234 pediatric patients diagnosed with COVID-19 were analyzed between August 2020 and September 2021 to evaluate the correlation between laboratory findings and disease severity.
- Key findings showed that thrombocytopenia, leukocytosis, lymphopenia, and D-dimer values are significant indicators of severe illness in children, highlighting their importance in patient evaluation.
Article Abstract
Background/aim: The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for generating a global pandemic with deadly consequences and life changes worldwide. With the appearance of the new variants of the virus, clinical manifestations have been reported in the pediatric population, some with severe evolution. The aim of this study was to identify the laboratory parameters necessary to establish an effective therapy.
Patients And Methods: In the period from August 2020 to September 2021, 234 pediatric patients met the inclusion criteria and were selected for the study. After confirming the COVID-19 diagnosis, laboratory parameters were analyzed and compared to the severity of the illness.
Results: Thrombocytopenia (p<0.001), leukocytosis (p<0.001), and lymphopenia (p<0.001) correlated with the severity of the disease. Also, D-dimer values were closely monitored due to the high association of this parameter with an unsatisfactory prognosis and a severe form of the disease.
Conclusion: The D-dimer values and complete blood count are useful parameters in COVID-19 evaluation in children.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9677791 | PMC |
| http://dx.doi.org/10.21873/invivo.13019 | DOI Listing |
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