AI Article Synopsis

  • Tuberculosis, primarily caused by Mycobacterium tuberculosis, remains a significant public health issue, with cutaneous tuberculosis being a rare but relevant form, often associated with HIV and multidrug-resistant cases.
  • A 32-year-old woman presented with a persistent foot ulcer, which did not improve with antibiotics but was later diagnosed as cutaneous tuberculosis after biopsy, and responded well to specific antitubercular treatment.
  • Accurate microbiological diagnosis is essential for cutaneous tuberculosis, which can mimic other skin conditions, and it should be considered in patients with chronic wounds that are resistant to standard treatments.

Article Abstract

Introduction And Importance: Tuberculosis is an age old disease caused by Mycobacterium tuberculosis which has been a menace to public health and thwarting economic growth. Pulmonary tuberculosis being the most common type, extra pulmonary tuberculosis has a greater association with HIV and multidrug resistant tuberculosis. Cutaneous tuberculosis accounts for 1-1.5 % of extra pulmonary tuberculosis.

Case Presentation: A 32 year old female presented to the outpatient department with a two month history of ulcer over the sole of the foot with multiple discharging sinuses and surrounding induration. Laboratory tests reported elevated total leukocyte counts. Magnetic Resonance Imaging of the foot showed diffuse intermuscular edema with an interconnecting sinus tract draining to the sole of the foot. Regular wound dressings and antibiotics showed no resolution. Patient eventually underwent near complete excision of the ulcer. The biopsy was suggestive of tuberculous etiology. She achieved complete resolution with antituberculous drugs by three months.

Clinical Discussion: Cutaneous tuberculosis is often misdiagnosed as it can masquerade as many other commonly encountered dermatological conditions. Microbiological diagnosis plays a crucial role in the accurate diagnosis of cutaneous tuberculosis. These lesions are highly responsive to antituberculous drugs.

Conclusion: Cutaneous tuberculosis is a rare disease that should be considered in the differential diagnosis of patients with chronic non-healing wounds that are poorly responsive to conventional treatment methods.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618970PMC
http://dx.doi.org/10.1016/j.ijscr.2022.107763DOI Listing

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