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The HET (history, electrocardiogram, and troponin) score has low efficacy and negative predictive value in a multisite U.S. cohort study.
Am J Emerg Med
December 2024
Department of Emergency Medicine, Wake Forest School of Medicine, Winston-Salem, NC, USA; Department of Epidemiology and Prevention, Wake Forest School of Medicine, Winston-Salem, NC, USA; Department of Implementation Science, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Introduction: The History, Electrocardiogram, and Troponin (HET) score is a simplified alternative to the HEART score for risk stratifying emergency department (ED) patients with chest pain. This study evaluates the safety and efficacy of the HET score for 30-day cardiac death or myocardial infarction (MI).
Methods: We conducted a secondary analysis of the STOP-CP multisite cohort study.
State Variation in Uptake of Pharmacy-Based CLIA-Waived Testing: Impact of Laws and Regulations.
J Pharm Technol
December 2024
College of Pharmacy, Ferris State University and Collaboration to Advance Pharmacy Enterprises, Grand Rapids, MI, USA.
Community pharmacies have grown to be an increasingly important provider of CLIA-waived tests, just second to physician offices as the venue with the most waivers. Yet, individual variation is still observed across states with respect to the percentage of pharmacies holding a CLIA-waiver, with a reported range of 10.7% in Massachusetts to 87.
View Article and Find Full Text PDFIntroduction: Methadone Maintenance Therapy (MMT) is commonly used to treat opioid addiction but can cause significant oral health issues, including poor oral hygiene, dental caries, periodontal disease, and bone resorption. These issues can negatively impact on overall quality of life, leading to both aesthetic and functional concerns.
Aim Of The Study: This research compares the oral health of individuals in methadone maintenance treatment (MMT) with those starting MMT.
Salinity modulation of neodymium and dysprosium toxicity in mussels: A comprehensive analysis of adult and sperm responses.
Sci Total Environ
December 2024
Department of Biology & CESAM, University of Aveiro, 3810-193 Aveiro, Portugal. Electronic address:
Neodymium (Nd) and dysprosium (Dy) are among the most commonly used rare earth elements (REEs) worldwide, leading to their increased concentrations in aquatic environments, with potential impacts on organisms. Additionally, organisms are also subjected to environmental stressors, such as salinity shifts, which can not only directly impact their health but also modulate the impacts of contaminants. Therefore, this study aimed to evaluate the effects of Nd and Dy on adult mussels and sperm of the species Mytilus galloprovincialis after 28 days and 30 min of exposure, respectively.
View Article and Find Full Text PDFLarge Language Models May Help Patients Understand Peer-Reviewed Scientific Articles About Ophthalmology: Development and Usability Study.
J Med Internet Res
December 2024
Stein Eye Institute, Department of Ophthalmology, David Geffen School of Medicine, Los Angeles, CA, United States.
Background: Adequate health literacy has been shown to be important for the general health of a population. To address this, it is recommended that patient-targeted medical information is written at a sixth-grade reading level. To make well-informed decisions about their health, patients may want to interact directly with peer-reviewed open access scientific articles.
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