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Diphtheria antitoxin treatment: from pioneer to neglected.
Mem Inst Oswaldo Cruz
January 2025
Institut Pasteur, Université Paris Cité, Biodiversity and Epidemiology of Bacterial Pathogens, Paris, France.
Diphtheria, a severe respiratory infection, was a major killer of children until the early years of the 20th century. Although diphtheria is now largely controlled globally thanks to vaccination, it is still endemic in some world regions and large epidemics can occur where vaccination coverage is insufficient. The pathological effects caused by its main virulence factor, diphtheria toxin, can be diminished by passive transfer of antibodies.
View Article and Find Full Text PDF"The living need care": Experiences of bereaved workers in precarious employment.
Death Stud
January 2025
University of Toronto, Toronto, Canada.
Bereavement scholarship predominantly examines psychological aspects of grief, which neglects the role of social, economic, and political factors that shape the space to accommodate these experiences. Responding to calls for enhancing bereavement care, this research explores bereavement accommodation for workers in precarious employment in Ontario, Canada. Drawing on critical qualitative research and feminist ethics, this study employed in-depth interviews to generate knowledge on the everyday experiences of bereaved workers in precarious employment.
View Article and Find Full Text PDFDiscrepancy between performance and feedback affects mathematics student teachers' self-efficacy but not their self-assessment accuracy.
Front Psychol
January 2025
Department of Educational Science, University of Freiburg, Freiburg, Germany.
Although feedback is of high importance for the professional development of student teachers, the impact of (inadequate) feedback on their self-regulated learning is still unclear. In two studies with mathematics student teachers, we investigated how discrepancies between performance and feedback affected two important aspects of self-regulated learning-self-efficacy and self-assessment accuracy regarding mathematical content knowledge. In the first study, = 154 student teachers studying mathematics completed a knowledge test on the Pythagorean theorem and received performance feedback that was either correct or manipulated to be more positive or more negative than actual performance.
View Article and Find Full Text PDFDiversity patterns and knowledge gaps of Atlantic Forest epiphyllous bryophytes: a highly neglected group.
Ann Bot
January 2025
Laboratório de Ecologia e Biogeografia de Plantas, Departamento de Biodiversidade, Setor Palotina, Universidade Federal do Paraná, Rua Pioneiro, 2153, Jardim Dallas, CEP 85950 000, Palotina, Paraná, Brazil.
Background: Epiphyllous bryophytes are a group of plants with complex adaptations to colonize the leaves of vascular plants and are considered one of the most specialized and sensitive groups to environmental changes. Despite their specificity and ecological importance, these plants represent a largely neglected group in relation to scientific research and ecological data. This lack of information directly affects our understanding of biodiversity patterns and compromises the conservation of this group in threatened ecosystems.
View Article and Find Full Text PDFEverything you ever wanted to know about cancer stem cells in neuroendocrine neoplasms but were afraid to ask.
Endocr Oncol
January 2024
Centro de Investigación Biomédica en Red, CIBERONC, ISCIII, Madrid, Spain.
While the role of cancer stem cells (CSCs) in tumorigenesis, chemoresistance, metastasis, and relapse has been extensively studied in solid tumors, such as adenocarcinomas or sarcomas, the same cannot be said for neuroendocrine neoplasms (NENs). While lagging, CSCs have been described in numerous NENs, including gastrointestinal and pancreatic NENs (PanNENs), and they have been found to play critical roles in tumor initiation, progression, and treatment resistance. However, it seems that there is still skepticism regarding the role of CSCs in NENs, even in light of studies that support the CSC model in these tumors and the therapeutic benefits of targeting them.
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