The global outbreak of coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus type 2 has prompted the rapid spread and development of vaccines to prevent the spread of the disease. COVID-19 vaccine has demonstrated excellent efficacy in reducing morbidity and severity of the disease, and most adverse reactions are very minor. However, some patients have been reported to develop autoimmune diseases, such as rheumatoid arthritis, myocarditis, Guillain-Barre syndrome, and vasculitis, following COVID-19 vaccination. Herein, we present a case of polyarteritis nodosa with epididymitis, following COVID-19 mRNA vaccination. The patient's initial symptoms were fever and testicular pain, and magnetic resonance imaging showed epididymitis. He was diagnosed as having polyarteritis nodosa with epididymitis and was treated with high-dose prednisolone, with a good clinical outcome.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9620383PMC
http://dx.doi.org/10.1093/mrcr/rxac085DOI Listing

Publication Analysis

Top Keywords

polyarteritis nodosa
12
nodosa epididymitis
12
case polyarteritis
8
epididymitis covid-19
8
covid-19 vaccination
8
vaccination case
8
disease covid-19
8
covid-19
5
epididymitis
4
case report
4

Similar Publications

Background: Polyarteritis nodosa is a relatively uncommon type of systemic necrotizing vasculitis that primarily affects medium-sized arteries. While gastrointestinal involvement is known in polyarteritis nodosa, heavy gastrointestinal bleeding due to gastric ulceration is relatively uncommon. We present the case of an 81-year-old male of Chinese ethnicity who experienced severe gastrointestinal bleeding as a result of polyarteritis nodosa and an innovative treatment approach for a better patient outcomes.

View Article and Find Full Text PDF

Polyarteritis nodosa (PAN) is a rare systemic necrotizing vasculitis that can lead to the formation of refractory lower limb ulcers requiring amputation. The standard treatment for severe PAN involves combination therapy with steroids and cyclophosphamide; however, some cases prove to be challenging. Recently, case reports have described the use of biological agents for PAN treatment.

View Article and Find Full Text PDF

The patient was a 48-year-old man who had developed acute myocardial infarction 3 years earlier. He started experiencing recurrent attacks of abdominal pain 2 years earlier. One month before the presentation, he developed perforative peritonitis, which was treated with right hemicolectomy.

View Article and Find Full Text PDF
Article Synopsis
  • The study investigates the effectiveness of a new imaging technique, fluorine-18-labeled FAP inhibitor (FAPI-42), for detecting systemic vasculitis in patients, comparing it to the standard FDG imaging technique.
  • A retrospective analysis of 30 patients revealed that FAPI-42 had a higher detection rate for lesions (100% vs. 93.3%) and identified more lesions overall compared to FDG (161 vs. 145).
  • FAPI-42 also showed a moderate correlation with inflammatory markers, suggesting it may be a valuable tool for assessing systemic vasculitis severity.
View Article and Find Full Text PDF

The deficiency of adenosine deaminase 2 (DADA2) is an autosomal recessive disorder caused by loss of function mutations in the ADA2 gene (previously the CECR1 gene) on chromosome 22q11. The clinical spectrum of the disease is remarkably broad, and its presentations mimic features of polyarteritis nodosa, such as livedoid rash, hematological abnormalities (e.g.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!