Airborne transmission of disease is of concern in many indoor spaces. Here, aerosol dispersion and removal in an unoccupied 4-bed hospital room were characterized using a transient aerosol tracer experiment for 38 experiments covering 4 configurations of air purifiers and 3 configurations of curtains. NaCl particle (mass mean aerodynamic diameter ~3 μm) concentrations were measured around the room following an aerosol release. Particle transport across the room was 1.5-4 min which overlaps with the characteristic times for significant viral deactivation and gravitational settling of larger particles. Concentrations were close to spatially uniform except very near the source. Curtains resulted in a modest increase in delay and decay times, less so when combined with purifiers. The aerosol decay rate was in most cases higher than expected from the clean air delivery rate, but the reduction in steady-state concentrations resulting from air purifiers was less than suggested by the decay rates. Apparently, a substantial (and configuration-dependent) fraction of the aerosol is removed immediately, and this effect is not captured by the decay rate. Overall, the combination of curtains and purifiers is likely to reduce disease transmission in multi-patient hospital rooms.
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http://dx.doi.org/10.1111/ina.13110 | DOI Listing |
Health Phys
January 2025
National Institute for Radiological Protection, Chinese Center for Disease Control and Prevention, Beijing, 100088, China.
Inhalation of 131I is the main route for internal doses to nuclear medicine workers. This study aimed to establish a simple analysis method for determining 131I activity in carbon cartridges, explore the activity concentration of 131I in nuclear medicine departments, and evaluate the internal dose of workers. A total of 21 nuclear medicine departments in the hospital conducted air sampling using a high-volume air sampler equipped with carbon cartridges and glass fiber filters to collect gaseous 131I and aerosol 131I, respectively.
View Article and Find Full Text PDFEClinicalMedicine
January 2025
WEISS Centre, University College London, UK.
Background: The COVID-19 pandemic highlighted the need for improved infectious aerosol concentrations through interventions that reduce the transmission of airborne infections. The aims of this review were to map the existing literature on interventions used to improve infectious aerosol concentrations in hospitals and understand challenges in their implementation.
Methods: We reviewed peer-reviewed articles identified on three databases, MEDLINE, Web of Science, and the Cochrane Library from inception to July 2024.
J Expo Sci Environ Epidemiol
January 2025
Department of Environmental and Occupational Health, Joe C. Wen School of Population & Public Health, University of California, Irvine, CA, USA.
Background: Children living in communities with lower socioeconomic status and higher minority populations are often disproportionately exposed to particulate matter (PM) compared to children living in other communities.
Objective: We assessed whether adding HEPA filter air cleaners to classrooms with existing HVAC systems reduces indoor air pollution exposure.
Methods: From July 2022 to June 2023, using a block randomized crossover trial of 17 Los Angeles Unified School District elementary schools, classroom PM concentrations were monitored and compared for 99 classrooms with HEPA filter air cleaners and 87 classrooms with non-HEPA filter air cleaners.
Environ Int
January 2025
Blue Growth Research Lab, Ghent University, Wetenschapspark 1, Bluebridge, 8400 Oostende, Belgium. Electronic address:
Sea spray aerosol (SSA) is a complex mixture of natural substances that can be inhaled by coastal residents. Previous studies have suggested that SSA may have positive effects on human health, but the molecular mechanisms and the factors influencing these effects are poorly understood. In this study, we exposed human bronchial epithelial cells (BEAS-2B) to natural SSA samples, collected monthly using quartz microfiber filters mounted on tripods within 15 m of the waterline, with air drawn through pumps, throughout a one-year period at the Ostend coast, Belgium, and measured cellular gene expression changes using RNA sequencing.
View Article and Find Full Text PDFOphthalmologie
January 2025
Klinik für Augenheilkunde, Universitätsklinikum Düsseldorf, Moorenstr. 5, 40225, Düsseldorf, Deutschland.
Background: The ocular surface is directly exposed to environmental influences. Noxae that have already been identified for the ocular surface are heat, air dryness, pollutant gases, fine dust particles and ultraviolet radiation.
Methods: The current literature was used to investigate the relationship between frequent ocular surface diseases and various environmental factors and to analyze their development over the years.
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