Broncholithiasis mimicking lung cancer.

Turk Gogus Kalp Damar Cerrahisi Derg

Department of Chest Diseases, Yedikule Chest Diseases and Thoracic Surgery Training and Research Hospital, Istanbul, Türkiye.

Published: July 2022

A 64-year-old female patient was admitted to our outpatient clinic with pleuritic chest pain, non-productive cough, and dyspnea. She expectorated three stones (lithoptysis) before bronchoscopy. She underwent positron emission tomography-computed tomography, which revealed a hyper metabolic mass in the right upper lobe of her lung. Three months later, the mass formation appeared as a patchy consolidation in the first control thoracic computed tomography examination. In conclusion, postobstructive consolidation due to broncholithiasis, which is very rare, should be kept in mind in the differential diagnosis of hyper metabolic mass. The simplest incidental diagnostic finding of broncholithiasis is the rare lithoptysis.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9580291PMC
http://dx.doi.org/10.5606/tgkdc.dergisi.2022.20482DOI Listing

Publication Analysis

Top Keywords

hyper metabolic
8
metabolic mass
8
broncholithiasis rare
8
broncholithiasis mimicking
4
mimicking lung
4
lung cancer
4
cancer 64-year-old
4
64-year-old female
4
female patient
4
patient admitted
4

Similar Publications

Introduction: Low-grade myofibroblastic sarcoma (LGMS) is an atypical and extremely infrequent type of tumor, primary mass being usually present in subcutaneous and soft tissue. Bony involvement is very rare. It has a very high chance of recurrence locally due to its aggressive biological behavior, metastasis in other parts of body is rarely seen.

View Article and Find Full Text PDF

Elevated glucose levels at the fetal-maternal interface are associated with placental trophoblast dysfunction and increased incidence of pregnancy complications. Trophoblast cells predominantly utilize glucose as an energy source, metabolizing it through glycolysis in the cytoplasm and oxidative respiration in the mitochondria to produce ATP. The TGFβ1/SMAD2 signaling pathway and the transcription factors PPARγ, HIF1α, and AMPK are key regulators of cell metabolism and are known to play critical roles in extravillous trophoblast cell differentiation and function.

View Article and Find Full Text PDF

Many bacteriophages modulate host transcription to favor expression of their own genomes. Phage satellite P4 polarity suppression protein, Psu, a building block of the viral capsid, inhibits hexameric transcription termination factor, ρ, by presently unknown mechanisms. Our cryogenic electron microscopy structures of ρ-Psu complexes show that Psu dimers clamp two inactive, open ρ rings and promote their expansion to higher-oligomeric states.

View Article and Find Full Text PDF

Polyploidy is a common outcome of chemotherapies, but there is conflicting evidence as to whether polyploidy is an adverse, benign or even favourable outcome. We show Aurora B kinase inhibitors efficiently promote polyploidy in many cell types, resulting in the cell cycle exit in RB and p53 functional cells, but hyper-polyploidy in cells with loss of RB and p53 function. These hyper-polyploid cells (>8n DNA content) are viable but have lost long-term proliferative potential in vitro and fail to form tumours in vivo.

View Article and Find Full Text PDF

Gestational diabetes mellitus-derived miR-7-19488 targets PIK3R2 mRNA to stimulate the abnormal development and maturation of offspring-islets.

Life Sci

January 2025

Department of Pharmacology, School of Pharmacy, Qingdao University, No. 308 Ningxia Road, Shinan District, Qingdao 266021, China; Key Laboratory of Maternal & Fetal Medicine of National Health Commission of China, Shandong Provincial Maternal and Child Health Care Hospital Affiliated to Qingdao University, Jinan 250014, China. Electronic address:

Aims: Gestational diabetes mellitus (GDM) provides offspring with a hyper-metabolic intrauterine microenvironment. In this study, we aimed to identify key differential microRNAs in GDM-derived exosomes and explore the potential mechanisms of abnormal embryonic development of islets in offspring.

Main Methods: Exosomes were extracted from umbilical vein blood of GDM and non-GDM (NGDM) parturients for microRNA sequencing.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!