Background: Domestic and parental occupational pesticide exposures are suspected of involvement in the occurrence of childhood acute leukaemia (AL), but the role of exposure to agricultural activities is little known. In a previous ecological study conducted in France, we observed an increase in acute lymphoblastic leukaemia (ALL) incidence rate with increasing viticulture density in the municipalities of residence at diagnosis.
Objectives: This study aimed to test the hypothesis that residential proximity to croplands at birth increases the risk of childhood AL, with a particular focus on vineyards.
Methods: We identified all the primary AL cases diagnosed before the age of 15 years in the cohorts of children born in the French municipalities between 1990 and 2015. We estimated crop densities in each municipality of residence at birth using agricultural census data, for ten crop types. Variations in standardized incidence ratios (SIR) were evaluated with Poisson regression models, for all AL, ALL and acute myeloid leukaemia (AML), separately.
Results: Among the 19,809,700 children born and residing in mainland France at birth in 1990-2015, 8,747 AL cases (7,236 ALL and 1,335 AML) were diagnosed over the period. We did not evidence any statistically significant positive association between total crop density or any specific crop density in the municipality of residence at birth and all AL, ALL or AML. Interestingly, we observed a higher ALL incidence rate in the municipalities with the highest viticulture densities (SIR = 1.25 95%CI [1.01-1.54]). Adjusting for the main potential confounders did not change the results.
Conclusion: Our study does not support the hypothesis that residential proximity to croplands, particularly vineyards, around birth plays a role in childhood leukaemia. The slightly higher ALL incidence rate in children born in the municipalities with the highest viticulture densities may reflect the previously-observed association at diagnosis.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9615229 | PMC |
| http://dx.doi.org/10.1186/s12940-022-00909-0 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Assessing the impact of railway noise on human health and daily life: a structural equation model approach for transportation and environmental planning.
Environ Monit Assess
December 2024
Department of Civil Engineering, National Institute of Technology, Warangal, 506004, Telangana, India.
Rapid urbanization has led to unplanned settlements near railway lines, exposing residents to continuous noise pollution with potential adverse effects on health. This study focuses on the environmental monitoring and assessment of railway noise pollution in urban areas and its impact on human health and daily activities. Noise levels were quantified across different residential zones using precise sound level meters, and a detailed human perception survey was conducted to assess the relationship between noise exposure, annoyance, and health disturbances.
View Article and Find Full Text PDFExploring urban scenarios of individual residential waste sorting using a spatially explicit agent-based model.
Waste Manag
December 2024
Department of Architecture and Civil Engineering, Chalmers University of Technology, 412 96 Gothenburg, Sweden.
Managing the diverse waste fractions generated by households presents a significant environmental and logistical challenge. One widely adopted solution is waste sorting at the source, where residents are required to separate their waste into designated containers. The success of this strategy depends on the extent of adoption and the behaviour of residents.
View Article and Find Full Text PDFUnlocking insights in real estate markets: Integrating geo-spatial data for comprehensive property valuation and urban planning.
Data Brief
December 2024
Department of Business Administration, Serkan Catma, University of South Carolina Beaufort, Bluffton, SC 29910, USA.
This article summarizes a database for analyzing the impact of structural and environmental characteristics on residential property values in Hamilton County, TN. The original dataset consists of house characteristics data for 873 residential sales between January 1, 2023, and September 25, 2023. Using Google's API tools and Point to Edge computations, several geographical variables-including the distance to green recreational areas, surrounding facilities, restaurants, air quality index, walk score-were gathered.
View Article and Find Full Text PDFBiomonitoring of toxic metal exposure in New Jersey adults in 2015-2018.
Int J Hyg Environ Health
December 2024
Environmental and Chemical Laboratory Services, Public Health & Environmental Laboratories, New Jersey Department of Health, Ewing, NJ, 08628, USA. Electronic address:
This study explores the potential of a convenience sample-based probing approach as a cost-effective alternative for state-level biomonitoring surveillance, addressing the logistical and practical challenges when applying comprehensive probability-based population studies at a state-level. The New Jersey Department of Health (NJDOH) conducted a large-scale biomonitoring study using 2988 blood samples and 1007 urine samples collected from clinical laboratories and blood banks statewide from 2015 to 2018 to characterize toxic metal exposure patterns and trends. The resulting data were analyzed to identify contributing factors and compared to concurrent U.
View Article and Find Full Text PDFPolychlorinated dibenzo-dioxin/furan and polychlorinated biphenyl concentrations in the human milk of individuals living near municipal waste incinerators in the UK: Findings from the Breast milk, Environment, Early-life, and development (BEED) human biomonitoring study.
Environ Res
December 2024
Department of Epidemiology and Biostatistics, Imperial College London, London, UK; NIHR Health Protection Research Unit on Chemical Radiation Threats and Hazards, Imperial College London, London, UK; MRC Centre for Environment and Health, Imperial College London, London, UK; National Institute for Health Research (NIHR) Health Protection Research Unit in Environmental Exposures and Health, Imperial College London, London, UK; Mohn Centre for Children's Health and Wellbeing, School of Public Health, Imperial College London, London, UK. Electronic address:
The objective of this study is to report recent PCDD/F and PCB human milk concentrations in the United Kingdom (UK) and relate these to two proxies for exposure to municipal waste incinerator (MWI) emissions. As part of the Breast milk, Environment, Early-life, and Development (BEED) study, primiparous individuals were recruited from within 20 km of English MWIs between 2013 and 2015 and asked to provide human milk samples. The samples were analysed for quantitative concentrations of 17 PCDD/F and 12 PCB congeners.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!