Phytochemical research of aerial parts led to isolation of 12 secondary metabolites, including one new 3-benzoxepin glucoside, perillafrutoside A (), one new megastigmane glycoside, perillafrutoside B (), and 10 known compounds. Their chemical structures were identified based on 1D/2D NMR, HRESIMS, and ECD spectroscopic analyses. The structure of was elucidated based on revision of the previously reported stereoisomer, (6,9)-blumenyl α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranoside. Evaluation of their antimicrobial effect revealed that compounds and inhibit growth, compounds , and suppress growth, whereas compounds and attenuate growth. This is the first report of the isolation of , and from the genus and the antimicrobial effect of compounds , and .
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