The misuse of substances by adolescents is a serious public health concern in the United States, and the three most used substances by adolescents are alcohol, cannabis, and electronic cigarettes. In accordance with the Social Development Model, a better understanding of the risk and protective factors across these three substances can assist in predicting potential substance use as well as strategies for prevention. The purpose of the current study is to examine the similar or differential influence that a specific set of risk and protective factors (i.e., favorable attitudes toward substance use, perceived risk of harm, peer substance use, interaction with prosocial peers, parental favorable attitudes toward substance use, family management, perceived availability substances, and rewards for prosocial involvement) have on past 30-day alcohol, cannabis, and e-cigarette use by adolescents. The present study is based on a secondary data analysis of the 2019 Prevention Needs Assessment Survey, which is administered every two years in the State of Utah to a large sample of students in grades 6, 8, 10, and 12 grades. A subsample of students (n = 44,728) was included in the present analysis. Logistic regression was used to examine the predictive relation for the set of four risk and four protective factors on past 30-day use of alcohol, cannabis, and e-cigarette use. In general, the results indicated that endorsement of the four risk factors predicted increases in the use of each substance whereas endorsement of the four protective factors predicted decreases in use. Implications of these findings suggest that there may be more similarities in risk and protective factors across alcohol, cannabis, and electronic cigarettes than between them. In addition, this study adds to the budding literature on the risk and protective factors associated with adolescent e-cigarette use.
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http://dx.doi.org/10.1007/s10935-022-00700-4 | DOI Listing |
BMC Med
January 2025
Department of Pharmaceutical Biosciences, Uppsala University, Box 593, Husargatan 3, Uppsala, 751 24, Sweden.
Background: Lifestyle choices, such as dietary patterns and sleep duration, significantly impact the health of the digestive system and may influence the risk of mortality from digestive system cancer.
Methods: This study aimed to examine the associations between sleep duration, dietary habits, and mortality from digestive system cancers. The analysis included 406,584 participants from the UK Biobank cohort (54.
Basic Clin Androl
January 2025
Chair of Endocrinology and Medical Sexology (ENDOSEX), Dept. of Systems Medicine, University of Rome Tor Vergata, via Montpellier 1, Rome, 00133, Italy.
The serendipitous discovery that inhibiting type 5 phosphodiesterase (PDE5) using sildenafil, a potent PDE5 inhibitor (PDE5i) initially developed for cardioprotection, introduced the possibility of orally managing erectile dysfunction (ED) led to an increase in research data, which are currently considered groundbreaking for the new discipline of sexual medicine. Findings from a number of laboratories and clinics around the world unanimously demonstrated the following: (i) the major cause of ED is directly or indirectly related to cardiovascular disease (CVD); (ii) ED and CVDs share the same risk factors, which are related mainly to lifestyle choices; (iii) the first therapeutic approach to both ED and CVDs is to transform harmful lifestyles into virtuous lifestyles; and (iv) PDE5is in general, particularly sildenafil, are very safe, if not protective, for use in CVD patients. However, the use of PDE5is has faced several challenges.
View Article and Find Full Text PDFLife Sci Space Res (Amst)
February 2025
Gulhane School of Medicine, Department of Obstetrics and Gynecology, Ankara, Turkey.
Space missions have revealed certain disincentive factors of this unique environment, such as microgravity, cosmic radiation, etc., as the aerospace industry has made substantial progress in exploring deep space and its impacts on human body. Galactic cosmic radiation (GCR), a form of ionizing radiation, is one of those environmental factors that has potential health implications and, as a result, may limit the duration - and possibly the occurrence - of deep-space missions.
View Article and Find Full Text PDFJ Mol Cell Cardiol
January 2025
Department of Physiology, University of Kentucky, Lexington, KY, USA; Department of Internal Medicine, University of Kentucky, Lexington, KY, USA. Electronic address:
Cardiologists have analyzed daily patterns in the incidence of sudden cardiac death to identify environmental, behavioral, and physiological factors that trigger fatal arrhythmias. Recent studies have indicated an overall increase in sudden cardiac arrest during daytime hours when the frequency of arrhythmogenic triggers is highest. The risk of fatal arrhythmias arises from the interaction between these triggers-such as elevated sympathetic signaling, catecholamine levels, heart rate, afterload, and platelet aggregation-and the heart's susceptibility (myocardial substrate) to them.
View Article and Find Full Text PDFExp Gerontol
January 2025
Department of Obstetrics and Gynecology, Affiliated Hospital of Jiangnan University, Wuxi City, Jiangsu Province, China. Electronic address:
Background: Frailty is an important predictor of poor postoperative outcomes in elderly patients with gynaecologic cancer. However, the prevalence and risk factors for frailty in this population remain unclear.
Methods: This cross-sectional study was conducted simultaneously in three gynecology departments of a tertiary hospital in China between January and March 2024.
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