A 37-year-old man was referred to the Emergency Department of the FundashonMariadal hospital in Bonaire because of an abnormal color of urine after having exercised heavily. Laboratory tests showed rhabdomyolysis with a creatine kinase level of 112.114 U/L. After hyperhydration creatine kinase values decreased rapidly, renal function remained normal.
Objectives: Window entrapment in cats can lead to reduced blood flow to the spinal cord, muscles and nerves, resulting in ischaemic neuromyelomyopathy. The severity and duration of entrapment greatly influence clinical and neurological outcomes, as well as prognosis. The aim of the present retrospective multicentric study (2005-2022) was to describe clinical, neurological and selected clinicopathological findings, as well as the outcome of cats trapped in bottom-hung windows, presented to both first-opinion and referral-only clinics.
Grossly lipaemic samples are a significant cause of analytical errors, potentially impacting patient care. The causes of lipaemia are varied and often unavoidable, while methods to reduce lipaemia through gold-standard ultracentrifugation are limited by availability, transportation, and cost. Benchtop centrifugation has been proposed as an alternative method to reduce lipaemia.
Rhabdomyolysis, a severe condition marked by the breakdown of muscle tissue, leads to the release of intracellular contents into the bloodstream. This condition can be triggered by a range of factors, including intense physical activity, traumatic injuries, certain medications, and infections. Diagnosis typically involves detecting elevated creatine phosphokinase (CPK) levels alongside characteristic clinical symptoms.
Adult-onset Still's disease (AOSD) is an uncommon systemic inflammatory disorder that presents with diverse, overlapping symptoms, complicating the diagnostic process due to its nonspecific clinical features and the absence of a definitive diagnostic test. Diagnosis is often challenging and relies on excluding other conditions while maintaining a high index of suspicion, supported by specific diagnostic criteria such as Yamaguchi or Fautrel. Prompt recognition and a multidisciplinary approach are essential, as AOSD can progress to life-threatening multiorgan dysfunction due to a hyperinflammatory response.
Background: Sevoflurane (Sevo) prevents hypoxia/reoxygenation (H/R)-induced cardiomyocytes injury. The expression of miR-4,454 was increased in individuals experiencing an acute myocardial infarction.
Objective: The purpose of current investigation was to delved into whether the effects of Sevo on cardiomyocytes are mediated through regulation of miR-4,454 expression.
