Themes of discussions in the Special Issue of T Cell Immunity and HIV-1 Pathogenicity are outlined here [...].
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| http://dx.doi.org/10.3390/vaccines10101624 | DOI Listing |
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AIP56, an AB toxin secreted by subsp. , has tropism for myeloid cells.
Front Immunol
January 2025
Fish Immunology and Vaccinology Group, Instituto de Biologia Molecular e Celular (IBMC), Universidade do Porto, Porto, Portugal.
Introduction: The AB-type toxin AIP56 is a key virulence factor of Photobacterium damselae subsp. piscicida (Phdp), inducing apoptosis in fish immune cells. The discovery of AIP56-like and AIP56-related toxins in diverse organisms, including human-associated Vibrio strains, highlights the evolutionary conservation of this toxin family, suggesting that AIP56 and its homologs may share conserved receptors across species.
View Article and Find Full Text PDFThe dilemma of X-linked agammaglobulinemia carriers.
J Allergy Clin Immunol Glob
February 2025
Department of Molecular Medicine, Sapienza University, Rome, Italy.
Background: Many patients with X-linked agammaglobulinemia (XLA) nowadays have reached adulthood, as well as their sisters, possibly carriers of a deleterious Bruton tyrosine kinase variant. Studies on motherhood outcomes in families with XLA are lacking.
Objective: We sought to investigate adherence to carrier status screening, interest in preconception and prenatal genetic counseling, and reproductive decisions in relatives with XLA.
Computational epitope-based vaccine design with bioinformatics approach; a review.
Heliyon
January 2025
Tehran Azad University of Medical Sciences, Faculty of Pharmaceutical Sciences, Iran.
The significance of vaccine development has gained heightened importance in light of the pandemic. In such critical circumstances, global citizens anticipate researchers in this field to swiftly identify a vaccine candidate to combat the pandemic's root cause. It is widely recognized that the vaccine design process is traditionally both time-consuming and costly.
View Article and Find Full Text PDFPartial Loss of NEMO Function in a Female Carrier with No Incontinentia Pigmenti.
J Clin Med
January 2025
Department of Systems Medicine, University of Rome Tor Vergata, 00133 Rome, Italy.
: The nuclear factor (NF)-kB essential modulator (NEMO) has a crucial role in the NFκB pathway. Hypomorphic pathogenic variants cause ectodermal dysplasia with immunodeficiency (EDA-ID) in affected males. However, heterozygous amorphic variants could be responsible for Incontinentia Pigmenti (IP) in female carriers.
View Article and Find Full Text PDFUse of Immunostimulants in Shrimp Farming-A Bioeconomic Perspective.
Animals (Basel)
January 2025
Immunology & Vaccinology Group, Centro de Investigaciones Biológicas del Noroeste (CIBNOR), Av. Instituto Politécnico Nacional 195, Playa Palo de Santa Rita Sur, La Paz 23096, Mexico.
Aquaculture is the fastest-growing food industry worldwide because it allows faster intensive production in a limited space and short time. However, the trade-off of this production scheme has led to infectious disease outbreaks that harm food production with economic impacts. Immunostimulants have entered the industry to fight against diseases by enhancing the immune system and conferring better protection against pathogens.
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