AI Article Synopsis
- The study focused on identifying virulent serovars, including those producing ESBLs, in both broiler chickens and humans through the examination of fecal samples.
- A total of 300 broiler and 360 human samples were analyzed, revealing a 10% recovery rate for broilers and 23.4% for humans, with a notable presence of multidrug-resistant strains.
- Findings highlighted genetic similarities in resistance genes between chicken and human isolates, suggesting a potential zoonotic risk and implications for public health.
Article Abstract
This study aimed to detect the virulent serovars (including ESBLs producing) isolated from broiler chickens and humans. Three hundred broilers and sixty human fecal samples were bacteriologically examined. Thirty (10%) and fourteen (23.4%) isolates were recovered from broiler and human samples, respectively. The most predominant serovar was and . All isolates were confirmed by conventional PCR-based A and A genes. Multidrug resistant (MDR) isolates were screened for the detection of A and D biofilm-associated genes, which were found in all isolated serovars except one and 2 of chicken isolates that were devoid of the A gene. Moreover, MDR isolates were screened for detection of seven resistance genes including ESBLs and other classes of resistance genes. Chicken isolates harbored , 1, and S genes as 100, 27.8, 11.1 and 11.1%, respectively, while all human isolates harbored , 1 and 3 genes. The genetic correlations between virulent serovars (including antimicrobial resistance) avian and human origins were compared. In conclusion, the high prevalence of virulent ESBL producing serovars in broilers and humans with genetic correlations between them might be zoonotic and public health hazards.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9610193 | PMC |
| http://dx.doi.org/10.3390/pathogens11101196 | DOI Listing |
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