AI Article Synopsis
- A case study reports a rare instance of high-grade endometrioid stromal sarcoma developing from a mature cystic teratoma in a 62-year-old woman, who had symptoms of lower abdominal pain for six months.
- Imaging revealed two masses indicating possible mature cystic teratomas, with one showing signs of malignancy, leading to a diagnosis of stage IIIC cancer post-surgery.
- Despite receiving chemotherapy after debulking surgery, the cancer recurred within three months, highlighting the importance of awareness among clinicians regarding this rare and poor-prognosis condition.
Article Abstract
We report an extremely rare case of ovarian high-grade endometrioid stromal sarcoma arising from a mature cystic teratoma with clinicopathologic features, and then we briefly review the pertinent literature. A 62-year-old nulliparous woman presented with lower abdominal pain that had begun 6 months earlier. Magnetic resonance imaging showed two adnexal masses with fat components, which suggested that they were mature cystic teratomas. The eccentric thick rim of the left mass showed irregular invasion of the uterus, which was suggestive of malignancy. Positron emission tomography/computed tomography demonstrated high fluorodeoxyglucose uptake in the corresponding area. The patient underwent debulking cytoreductive surgery. The diagnosis was of an International Federation of Obstetrics and Gynecology stage IIIC high-grade endometrioid stromal sarcoma arising from a mature cystic teratoma. After surgery, the patient received adjuvant chemotherapy with three courses of doxorubicin regimen. The cancer recurred 3 months after surgery, and the patient died of progressive disease. It might be helpful for clinicians to be aware of this rare disease and the poor prognosis when it is at an advanced stage.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9610105 | PMC |
| http://dx.doi.org/10.3390/medicina58101501 | DOI Listing |
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