Nutraceuticals for Complementary Treatment of Multisystem Inflammatory Syndrome in Children: A Perspective from Their Use in COVID-19.

Life (Basel)

Área Académica de Enfermería, Instituto de Ciencias de la Salud, Universidad Autónoma del Estado Hidalgo, Circuito Ex Hacienda La Concepción S/N, Carretera Pachuca-Actopan, San Agustín Tlaxiaca 42160, Mexico.

Published: October 2022

AI Article Synopsis

  • MIS-C is a serious inflammatory condition that can occur in children 2 to 4 weeks after infection with SARS-CoV-2, characterized by inflammation and heart issues.
  • Despite being recognized for over two years, effective treatments for MIS-C are still being studied.
  • The review explores the potential of natural compounds that have antioxidant and anti-inflammatory properties as possible treatments to mitigate hyperinflammation associated with MIS-C.

Article Abstract

Multisystem inflammatory syndrome in children (MIS-C) has been widely reported in some children diagnosed with SARS-CoV-2. Clinical signs of MIS-C are manifested at 2 to 4 weeks after SARS-CoV-2 infection, where elevated biomarkers of inflammation and cardiac dysfunction are the hallmark of this syndrome when infection or exposure to SARS-CoV-2 has been confirmed. However, after two years of acknowledgment, MIS-C treatment is still under research to reach safety and effectiveness in the acute phase in children. Therefore, in this review, we discuss the potential use of natural compounds with antioxidant and anti-inflammatory effects to reduce collateral damage caused by hyperinflammation in MIS-C pathology for new research in treatment and interventions.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9605437PMC
http://dx.doi.org/10.3390/life12101652DOI Listing

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