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Intravesical Gentamicin: An Option for Therapy and Prophylaxis against Recurrent UTIs and Resistant Bacteria in Neurogenic Bladder Patients on Intermittent Catheterization. | LitMetric
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Intravesical Gentamicin: An Option for Therapy and Prophylaxis against Recurrent UTIs and Resistant Bacteria in Neurogenic Bladder Patients on Intermittent Catheterization.

Elena Andretta Raffaele Longo Massimo Balladelli Camilla Sgarabotto Dino Sgarabotto

Antibiotics (Basel)

Abano Infectious Diseases Outpatient Clinic, 35031 Padova, Italy.

Published: September 2022

AI Article Synopsis

  • The study examines the use of Gentamicin, delivered directly into the bladder, for treating and preventing UTIs in patients with neurogenic bladders who need regular catheterization.
  • It highlights Gentamicin as a viable alternative when other standard systemic treatments for UTIs have not worked.
  • The use of Gentamicin in this manner is considered off-label, meaning it’s not officially approved for this specific purpose but has shown promise in clinical practice.

Article Abstract

This is a retrospective study of our experience with Gentamicin intravesical instillation as therapy and prophylaxis in patients with lower urinary tract infections (UTIs) undergoing clean intermittent catheterization because of a neurogenic bladder. It is an alternative therapy when all other systemic treatments have failed as it is still an off-label prescription.

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 Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598998PMC
http://dx.doi.org/10.3390/antibiotics11101335DOI Listing

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