AI Article Synopsis
- Tick-borne encephalitis virus (TBEV) was first identified in the Netherlands in ticks in 2015 and in humans in 2016, prompting a study to assess its prevalence.
- During extensive surveillance from 2018 to 2020, researchers tested over 46,000 ticks and 320 rodents at high-risk locations.
- The findings revealed low infection rates in rodents and ticks, evidence of three TBEV variants circulating, indicating a broader distribution of the virus in the Netherlands than previously recognized.
Article Abstract
Tick-borne encephalitis virus (TBEV) is an emerging pathogen that was first detected in ticks and humans in the Netherlands in 2015 (ticks) and 2016 (humans). To learn more about its distribution and prevalence in the Netherlands, we conducted large-scale surveillance in ticks and rodents during August 2018-September 2020. We tested 320 wild rodents and >46,000 ticks from 48 locations considered to be at high risk for TBEV circulation. We found TBEV RNA in 3 rodents (0.9%) and 7 tick pools (minimum infection rate 0.02%) from 5 geographically distinct foci. Phylogenetic analyses indicated that 3 different variants of the TBEV-Eu subtype circulate in the Netherlands, suggesting multiple independent introductions. Combined with recent human cases outside known TBEV hotspots, our data demonstrate that the distribution of TBEV in the Netherlands is more widespread than previously thought.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9707572 | PMC |
| http://dx.doi.org/10.3201/eid2812.220552 | DOI Listing |
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