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Psychedelics for the Treatment of Psychiatric Disorders: Interpreting and Translating Available Evidence and Guidance for Future Research.
Am J Psychiatry
January 2025
Department of Psychiatry (McIntyre, Mansur, Rosenblat) and Department of Pharmacology and Toxicology (McIntyre, Mansur, Rosenblat), University of Toronto, Toronto; Brain and Cognition Discovery Foundation, Toronto (Kwan, Teopiz); Faculty of Medicine, University of Ottawa, Ottawa (Kwan); Champalimaud Research and Clinical Center, Champalimaud Foundation, Lisbon (Oliveira-Maia); NOVA Medical School, Faculdade de Ciências Médicas, NMS, FCM, Universidade NOVA de Lisboa, Lisbon (Oliveira-Maia); Department of Psychiatry and Behavioral Sciences, University of South Carolina School of Medicine, Greenville (Maletic); Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford (Suppes); Department of Psychiatry, University of California, San Diego (Stahl).
During the past decade, there has been extraordinary public, media, and medical research interest in psychedelics as promising therapeutics for difficult-to-treat psychiatric disorders. Short-term controlled trial data suggest that certain psychedelics are effective and safe in the treatment of major depressive disorder, treatment-resistant depression, and posttraumatic stress disorder. Preliminary evidence also supports efficacy in other psychiatric disorders (e.
View Article and Find Full Text PDFMechanism and strategy of self-assembly of quaternary ammonium surfactant molecules to regulate pesticide droplet impact and wetting of hydrophobic surfaces.
Pest Manag Sci
December 2024
Shanxi Key Laboratory of Integrated Management of Agricultural Pests, College of Plant Protection, Shanxi Agricultural University, Taiyuan, China.
Background: Surfactants regulate the interaction between pesticide droplets and the surfaces of plants on which they are sprayed. The influence of the key structural functional groups of surfactants on the interaction between pesticide droplets and hydrophobic pear leaves has not been explored. The behavior of Imidacloprid (Imid) droplets regulated by cationic quaternary ammonium surfactants with different structures on hydrophobic pear leaves and their bouncing dynamics were studied.
View Article and Find Full Text PDFThe impacts of climate change on the potential distribution of Cacopsylla chinensis (Hemiptera: Psyllidae) in China.
J Econ Entomol
November 2024
Shanxi Center for Testing of Functional Agro-Products, Shanxi Agricultural University, Taiyuan, PR China.
Cacopsylla chinensis is an oligophagous pest and has become one of the main pests that cause yield loss in commercial pear orchards in China. Predicting the impact of climate change on the distribution range of C. chinensis is crucial for its effectively preventing and managing.
View Article and Find Full Text PDFDisparities in Treatment for Alcohol Use Disorder Among All of Us Participants.
Am J Psychiatry
November 2024
Center for Value-Based Care Research, Cleveland Clinic (Le, Rich, Gasoyan, Rothberg) and Department of Pharmacy and Center for Geriatric Medicine, Cleveland Clinic, Cleveland, Ohio (Ayers); Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland (Rich); Department of General Internal Medicine, Massachusetts General Hospital, Boston (Bernstein); Kaiser Permanente Washington Health Research Institute, Seattle (Glass); Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, and Ralph H. Johnson VA Healthcare System, Charleston (Back); TSET Health Promotion Research Center, Stephenson Cancer Center, and Department of Family and Preventive Medicine, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City (Bui).
Objective: The authors examined racial/ethnic and socioeconomic disparities in receiving treatment for alcohol use disorder (AUD).
Methods: A retrospective cohort study was conducted that included adults (≥18 years) with AUD from the All of Us Controlled Tier database v7. Outcomes were lifetime receipt of FDA-approved medications (disulfiram, acamprosate, and naltrexone), psychotherapy (individual, family, and group-based session), and combination treatment (medication and psychotherapy).
Diffusive Phyllosphere Microbiome Potentially Regulates Harm and Defence Interactions Between Stephanitis nashi and Its Crabapple Host.
Plant Cell Environ
February 2025
Co-Innovation Center for Sustainable Forestry in Southern China, College of Forestry, Nanjing Forestry University, Nanjing, Jiangsu, China.
Pear lace bug (Stephanitis nashi) is a significant herbivorous pest, harbouring a diverse microbiome crucial for crabapple (Malus sp.) host adaptation. However, the mutual influence of S.
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