AI Article Synopsis
- A study in South Korea (2014-2019) found 27 cases of severe pneumonia caused by Corynebacterium striatum, mostly affecting hospital-acquired pneumonia patients.
- * About 70% of the cases were hospital-acquired, with over half of the patients being immunocompromised.
- * The proportion of C. striatum infections among severe hospital-acquired pneumonia cases increased, while MRSA infections declined, highlighting C. striatum's growing role as a serious pneumonia threat.
Article Abstract
We investigated the proportion and characteristics of severe Corynebacterium striatum pneumonia in South Korea during 2014-2019. As part of an ongoing observational study of severe pneumonia among adult patients, we identified 27 severe C. striatum pneumonia cases. Most (70.4%) cases were hospital-acquired, and 51.9% of patients were immunocompromised. C. striatum cases among patients with severe hospital-acquired pneumonia (HAP) increased from 1.0% (2/200) during 2014-2015 to 5.4% (10/185) during 2018-2019, but methicillin-resistant Staphylococcus aureus (MRSA) infections among severe HAP cases decreased from 12.0% to 2.7% during the same timeframe. During 2018-2019, C. striatum was responsible for 13.3% of severe HAP cases from which bacterial pathogens were identified. The 90-day mortality rates were similarly high in the C. striatum and MRSA groups. C. striatum was a major cause of severe HAP and had high mortality rates. This pathogen is emerging as a possible cause for severe pneumonia, especially among immunocompromised patients.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9622248 | PMC |
| http://dx.doi.org/10.3201/eid2811.220273 | DOI Listing |
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