Dinuclear osmium complexes as mitochondrion-targeting antitumor photothermal agents .

Chem Commun (Camb)

Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, Yunnan Provincial Center for Research & Development of Natural Products, School of Pharmacy, Yunnan University, Kunming, 650091, P. R. China.

Published: November 2022

Four dinuclear osmium complexes have been constructed for antitumor phototherapy. The most potent Os4 has extremely high photothermal conversion capability under irradiation of an 808 nm low-power laser, targets mitochondria in human melanoma cells without nucleus affinity, and acts as an antitumor photothermal therapy agent and .

Download full-text PDF

Source
http://dx.doi.org/10.1039/d2cc05230jDOI Listing

Publication Analysis

Top Keywords

dinuclear osmium
8
osmium complexes
8
antitumor photothermal
8
complexes mitochondrion-targeting
4
mitochondrion-targeting antitumor
4
photothermal agents
4
agents dinuclear
4
complexes constructed
4
constructed antitumor
4
antitumor phototherapy
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!