Building Information Modeling (BIM) has become the development trend in the architecture, engineering, and construction (AEC) industry. BIM discipline competition is an effective way for students of AEC-related disciplines to integrate theory with practice, and it is a key link to cultivate qualified BIM practitioners. This study takes participants of the 8th National College BIM Graduation Design Innovation Competition as the research objects. The Technology Acceptance Model and the Theory of Planned Behavior are combined to build a driving factor model of the competitions. Contestants of the competition were asked to complete online questionnaires, and 451 valid samples were finally obtained. Structural Equation Modeling was used to fit the theoretical model, and it was found that: Behavioral Intention to use BIM is directly and positively affected by Attitude, Perceived Behavioral Control, and Perceived Usefulness, as well as indirectly and positively affected by Perceived Usefulness and Perceived Eased of Usefulness. Competition Results is directly and positively affected by Behavioral Intention to use BIM, Perceived Behavioral Control, and Facilitating Conditions. It is also indirectly and positively affected by Attitude, Perceived Behavior Control, Perceived Usefulness, and Perceived Eased of Usefulness. The results show that the situation of students' participation in BIM competition can be optimized by increasing the publicity and promotion of BIM and related policies, strengthening the construction of supporting teaching facilities, building the integrated curriculum system of BIM technology, and strengthening teacher training. This study provides a theoretical reference for further BIM practice, and it would help improve the corresponding teaching organization and enhance the internal drive of students' BIM learning.
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http://dx.doi.org/10.3390/bs12100360 | DOI Listing |
Drug Deliv Transl Res
January 2025
i3S - Instituto de Investigação e Inovação em Saúde, University of Porto, Rua Alfredo Allen 208, 4200-135, Porto, Portugal.
Glioblastoma presents a significant treatment challenge due to the blood-brain barrier (BBB) hindering drug delivery, and the overexpression of matrix metalloproteinases (MMPs), which promotes tumor invasiveness. This study introduces a novel nanostructured lipid carrier (NLC) system designed for the delivery of batimastat, an MMP inhibitor, across the BBB and into the glioblastoma microenvironment. The NLCs were functionalized with epidermal growth factor (EGF) and a transferrin receptor-targeting construct to enhance BBB penetration and entrapment within the tumor microenvironment.
View Article and Find Full Text PDFSci Rep
December 2024
China 19T'' Metallurgical Group Corporation Limited, 610039, Chengdu, China.
As one of the primary precast components in prefabricated construction, composite slabs have increasingly attracted interest for their costs as well as carbon footprint in production and installation stages. Conventional methods for separating composite slabs can lead to a building project necessitating multiple specifications of composite slabs. Due to the requirement to customize molds for different modulus of composite slabs, the production process experiences a substantial rise in energy consumption and resource waste.
View Article and Find Full Text PDFChem Asian J
December 2024
Birla Institute of Technology & Science Pilani - Hyderabad Campus, Chemistry department, Shameerpet, 500078, Hyderabad, INDIA.
The incorporation of photoactive organic dyes into layered inorganic materials enhances their optical and chemical properties, making them ideal for sensing applications. In this study, Bisindolyl methane (BIM)-based neutral probes were integrated with bentonite clay to explore their sensing capabilities. Probe 1 (unoxidized BIM) and Probe 2 (oxidized BIM) generally exhibited quenched luminescence in solution due to intramolecular rotations.
View Article and Find Full Text PDFAnimal
November 2024
CLMT Research Group for Insect Production and Processing, Department of Microbial and Molecular Systems (M(2)S), KU Leuven, Geel Campus, Kleinhoefstraat 4, 2440 Geel, Belgium. Electronic address:
Black soldier fly larvae (BSFL, Hermetia illucens) contain high amounts of proteins and essential amino acids and are therefore an appropriate feed source. However, they lack essential fatty acids (FAs), specifically ω-3 and ω-6, making them a less desirable feed choice for aquaculture. The aim of this study was to increase the ω-3 and ω-6 FA concentrations in BSFL by manipulating the FA composition in their rearing substrate.
View Article and Find Full Text PDFFront Oncol
December 2024
Cansearch Research Platform for Pediatric Oncology and Hematology, Department of Pediatrics, Gynecology and Obstetrics, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Background: We previously demonstrated that APR-246 (eprenetapopt) could be an efficient treatment option against neuroblastoma (NB), the most common pediatric extracranial solid tumor. APR-246's mechanism of action is not completely understood and can differ between cell types. Here we investigate the involvement of well-known oncogenic pathways in NB's response to APR-246.
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