AI Article Synopsis

  • * The patient experienced symptoms like difficulty breathing and swallowing, with laryngoscopic findings of abnormal growths in the throat, which led to further testing.
  • * Diagnosis was confirmed based on local prevalence and exclusion of other granulomatous diseases, and treatment with anti-tuberculosis medication and steroids led to significant improvement in his symptoms within 40 days.

Article Abstract

Isolated laryngeal tuberculosis is rare and sometimes difficult to diagnose. It is the most common cause of laryngeal granuloma. We here report the case of a 58-year-old man, with no particular past medical history, hospitalized due to paroxysmal laryngeal dyspnea, dysphagia to solid foods and dysphonia evolving for 6 months without other associated signs. Laryngoscopic examination showed polyploid formation masking the glottic floor. Histological examination revealed epithelioid and gigantocellular granuloma, without caseous necrosis. Direct microscopic examination and culture were negative. The diagnosis of isolated laryngeal tuberculosis was made based on the endemicity in our country and the absence of other arguments in favor of another type of granulomatosis. Anti-tuberculosis therapy, combined with oral corticosteroids, was indicated based on the presence of severe upper airway edema and symptoms were resolved after 40 days of treatment.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9557792PMC
http://dx.doi.org/10.11604/pamj.2022.43.9.21014DOI Listing

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