A 24-hr electrocardiographic monitoring was performed in 406 patients (297 with ischemic heart disease). Forty-one episodes of ventricular tachycardia were detected in 32 subjects (7.88%). The average rate of tachycardia was 127.4 (range 180-65). No correlation was observed between the rate of ventricular tachycardia and the heart rate 30, 20, and 10 min before and at the moment of the episode. A circadian rhythm of all the episodes was demonstrated, with an acrophase at 1102 hr. A different acrophase was observed for the QT interval. No significant rhythm was observed for premature ventricular beats in the patients with ventricular tachycardia. The circadian variation of tachycardia suggests that this arrhythmia is related to sympathetic tone, but it will require further studies with a larger number of patients with ventricular tachycardia to clarify this problem.
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JACC Case Rep
January 2025
Department of Cardiovascular Magnetic Resonance, Hôpital Privé Jacques Cartier, Institut Cardiovasculaire Paris Sud, Massy, France.
Although relatively rare, cardiac metastases represent a significant clinical challenge because of their impact on cardiac function and overall patient prognosis. This case presents a rare and atypical presentation of a patient with ventricular arrhythmia revealing a metastatic cancer in the heart. A 59-year-old man with lung cancer was admitted for chest tightness and episodes of syncope.
View Article and Find Full Text PDFJACC Case Rep
January 2025
Division of Cardiology, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Structural abnormalities within the right ventricular outflow tract (RVOT) can present similarly to Brugada syndrome. A 34-year-old woman with no medical history presented with polymorphic ventricular tachycardia/ventricular fibrillation cardiac arrest and initial electrocardiogram showed type I Brugada pattern. Cardiac magnetic resonance imaging revealed prominent tissue thickening at the RVOT with late gadolinium enhancement.
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December 2024
Medical and Surgical unit of Congenital and Paediatric Cardiology, Reference Centre for Complex Congenital Heart Defects-M3C, University Hospital Necker-Enfants Malades, Paris, France.
Cardiac fibroma is the second most common childhood cardiac tumor. Coronary arteries are typically unaffected. A 5-month-old infant received a diagnosis of giant cardiac fibroma with coronary involvement.
View Article and Find Full Text PDFJACC Clin Electrophysiol
January 2025
Vanderbilt Heart and Vascular Institute, Nashville, Tennessee, USA. Electronic address:
Background: Programmed electrical stimulation (PES) is an essential part of ventricular tachycardia (VT) ablation procedures, but VT is not always inducible, usually for reasons that are not clear.
Objectives: This study sought to review pacing site-specific failure of PES to induce scar-related VT and to provide a potential mechanistic explanation of the phenomena using a computer simulation.
Methods: Six patients in whom aggressive PES from traditional RV pacing sites failed to induce VT, but VT was easily inducible from a nontraditional site, were reviewed.
JACC Clin Electrophysiol
January 2025
Division of Cardiovascular Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA. Electronic address:
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