The widespread use in today's world of radioactive sources d in energy, medicine, engineering and construction, for contaminant tracking and food sterilization increases the likelihood of accidental exposure. The use of ionizing radiation and radioactive elements can directly or indirectly cause life-threatening complications, such as oncopathology, radiation burns, and impaired immunity. Pollution of the environment with radioactive elements and depletion of the ozone layer also contribute to an increase in the level of radiation exposure. To protect the health of the population living in contaminated areas and consuming locally produced products, it is necessary to organize a system for monitoring radioactive damage, as well as special anti-radiation protective measures in the field of agriculture and forestry, hunting and fishing, and providing the population with food. The purpose of the study is to analyze modern scientific data on the effect of ionizing radiation on reproductive function and modern approaches aimed at correcting its violations. Bibliographic, information-analytical methods and methods of comparative analysis were used.
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http://dx.doi.org/10.32687/0869-866X-2022-30-5-771-775 | DOI Listing |
Clin Exp Dermatol
December 2024
Department of Dermatology, Medical University of Vienna, Vienna, Austria.
Background: Although ultraviolet radiation is the most important risk factor for skin cancer in general, its role in disease control after the diagnosis of melanoma remains to be elucidated.
Objectives: To analyse the association between survival and self-assessed sun protection behaviour after a melanoma diagnosis.
Methods: This was a questionnaire-based pilot study.
Transl Vis Sci Technol
December 2024
Department of Biomedical Engineering, University of Houston, Houston, TX, USA.
Purpose: To assess the safety of acoustic radiation force optical coherence elastography in the crystalline lens in situ.
Methods: Acoustic radiation force (ARF) produced by an immersion single-element ultrasound transducer (nominal frequency = 3.5 MHz) was characterized using a needle hydrophone and used for optical coherence elastography (OCE) of the crystalline lens.
Background: Intrathecally (IT) delivered antisense oligonucleotides (ASOs) are promising therapies that can reduce tau pathology in Alzheimer's Disease (AD). However, current plasma and CSF sampling methods to estimate brain tissue exposure of ASOs are inherently limited, hampering ASO clinical developmental plans. We developed the PET tracer [F]BIO-687, which binds ASO conjugates (ASO-Tz) in vivo, allowing us to image ASO distribution in a living brain using "pretargeted" imaging.
View Article and Find Full Text PDFHealth Phys
January 2025
Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300192, China.
The objective of this paper is to construct a follow-up cohort of medical x-ray workers and analyze the risk estimates of radiation-induced carcinogenic and noncarcinogenic diseases induced by chronic low-dose ionizing radiation exposure in the follow-up cohort. A fixed cohort study was used. A total of 159 medical x-ray workers working in radiology departments of hospitals in Gansu Province from 1950 to 1980 were selected as the radiology group, and 149 medical workers in internal medicine, surgery, and other departments who had not engaged in radiology work at the same hospital were selected as the control group.
View Article and Find Full Text PDFMol Carcinog
January 2025
Department of Neurosurgery, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, The People's Republic of China.
RNF7 (Ring Finger Protein 7) is a key component of CRLs (Cullin-RING-type E3 ubiquitin ligases) and has been found to possess intrinsic anti-ROS capabilities. Aberrant expression of RNF7 has been observed in various tumor types and is known to significantly influence tumor initiation and progression. However, the specific role of RNF7 in glioblastoma remains unclear.
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