Low socioeconomic status was associated with a higher mortality risk in multiple sclerosis.

Mult Scler

Department of Medicine, Division of Neurology and the Djavad Mowafaghian Centre for Brain Health, University of British Columbia, UBC Hospital, Vancouver, BC, Canada.

Published: March 2023

AI Article Synopsis

  • The study explores the link between socioeconomic status (SES) and mortality among people with multiple sclerosis (PwMS), highlighting a gap in understanding.
  • Researchers analyzed data from 12,126 MS patients diagnosed between 1994 and 2017, using a statistical model to evaluate the impact of SES on mortality risk.
  • Findings indicate that lower SES is significantly linked to higher mortality risk, with the most deprived individuals facing a mortality risk 61% higher than those least deprived.

Article Abstract

Background: The relationship between socioeconomic status (SES) and mortality among persons with multiple sclerosis (PwMS) is poorly understood.

Objective: To investigate the association between SES and mortality risk in PwMS.

Methods: From health-administrative data, we identified 12,126 incident MS cases with a first demyelinating event (MS 'onset') occurring between 1994 and 2017. Cox proportional hazard model assessed the association between socioeconomic status quintiles (SES-Qs) at MS onset and all-cause mortality.

Results: Lower SES-Qs were associated with higher mortality risk; adjusted hazard ratios: SES-Q1 (most deprived) =1.61 (95% confidence interval (CI) = 1.36-1.91); SES-Q2 = 1.26 (95% CI = 1.05-1.50); SES-Q3 = 1.22 (95% CI = 1.02-1.46); SES-Q4 = 1.13 (95% CI = 0.94-1.35) versus SES-Q5 (least deprived).

Conclusion: A lower SES was associated with higher mortality risk in PwMS.

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Source
http://dx.doi.org/10.1177/13524585221129963DOI Listing

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