AI Article Synopsis
- The study aimed to explore the connection between calcium metabolism-related factors and temporomandibular joint (TMJ) disk displacement with reduction (DDWR) among TMD patients and healthy controls.
- The research included 50 patients with TMD and 50 healthy individuals, examining various biochemical markers, revealing lower calcium levels and higher rates of severe vitamin D deficiency in the TMD group.
- The findings suggest that deficiencies in calcium and vitamin D might be linked to TMJ DDWR, indicating the need for evaluation and potential correction of these deficiencies in TMD patients.
Article Abstract
Objective: The aim of this study is to investigate the relationship between calcium metabolism-related biochemical factors (alkaline phosphatase, vitamin D, parathyroid hormone (PTH), calcium, phosphorus and magnesium), and temporomandibular joint (TMJ) disk displacement with reduction (DDWR).
Materials And Methods: This prospective observational study included patients with temporomandibular disorders (TMDs) (n = 50) and healthy controls (n = 50) of similar age and sex. The diagnosis of TMJ DDWR was made using the diagnostic criteria for temporomandibular joint disorders (DC/TMD). Both groups were compared in terms of serum alkaline phosphatase, 25 (OH) vitamin D, PTH, calcium, magnesium, and phosphorus levels. P<0.005 was accepted as a significant difference.
Results: There was no significant difference between the groups in terms of age, gender, and body mass index (BMI). Calcium levels of patients with TMD were statistically significantly lower than control patients (p<0.05). While there was no significant difference between the two groups in terms of mean VIT D, the number of people with severe Vit D deficiency (<10 ng) in the TMD group was significantly higher than in the control group (p<0.05). There was no statistically significant difference between the groups in terms of serum alkaline phosphatase, magnesium, phosphorus and PTH levels.
Conclusion: The differences in serum calcium and vitamin D levels seen in the study indicate that biochemical factors related to calcium metabolism may be associated with TMJ DDWR. These results suggest that calcium and vitamin D deficiency should be evaluated and corrected in patients with TMD.
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| http://dx.doi.org/10.1016/j.jormas.2022.10.014 | DOI Listing |
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