HLA-A*11:416 has one non-synonymous nucleotide change from A*11:01:01:01 in codon 39.
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DeepGOMeta for functional insights into microbial communities using deep learning-based protein function prediction.
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KAUST Center of Excellence for Smart Health (KCSH), King Abdullah University of Science and Technology, Thuwal, 23955, Saudi Arabia.
Analyzing microbial samples remains computationally challenging due to their diversity and complexity. The lack of robust de novo protein function prediction methods exacerbates the difficulty in deriving functional insights from these samples. Traditional prediction methods, dependent on homology and sequence similarity, often fail to predict functions for novel proteins and proteins without known homologs.
View Article and Find Full Text PDFDesign of an intelligent disinfection control system based on an STM32 single-chip microprocessor by using the YOLO algorithm.
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December 2024
College of Mechanical and Electronic Engineering, Dalian Minzu University, Dalian, 116650, Liaoning, China.
The novel coronavirus (COVID-19) has affected more than two million people of the world, and far social distancing and segregated lifestyle have to be adopted as a common solution in recent years. To solve the problem of sanitation control and epidemic prevention in public places, in this paper, an intelligent disinfection control system based on the STM32 single-chip microprocessor was designed to realize intelligent closed-loop disinfection in local public places such as public toilets. The proposed system comprises seven modules: image acquisition, spraying control, disinfectant liquid level control, access control, voice broadcast, system display, and data storage.
View Article and Find Full Text PDFInitial experience of a novel surgical assist robot "Saroa" featuring tactile feedback and a roll-clutch system in radical prostatectomy.
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Department of Urology, The Jikei University School of Medicine, Kashiwa Hospital, Kashiwashita 163-1, Kashiwa, Chiba, 277-8567, Japan.
To evaluate the safety and efficacy of the Saroa Surgical Robot System in robot-assisted laparoscopic radical prostatectomy (RARP). We enrolled 60 patients who underwent RARP using either the Saroa (n = 9) or da Vinci Xi (n = 51) systems at Jikei University Kashiwa Hospital from January 2022 to March 2024. We compared preoperative characteristics, perioperative outcomes, complications, and postoperative urinary continence at three months between the two groups.
View Article and Find Full Text PDFDCLRE1B as a novel prognostic biomarker associated with immune infiltration: a pancancer analysis.
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Department of Orthopedics, The Second Affiliated hospital, Jiangxi Medical College, Nanchang University, Nanchang, 330006, Jiangxi Province, China.
The DNA cross-link repair 1B (DCLRE1B) gene is involved in repairing cross-links between DNA strands, including those associated with Hoyeraal-Hreidarsson syndrome and congenital dyskeratosis. However, its role in tumours is not well understood. DCLRE1B expression profiles were examined in tumour tissues and normal tissues using TCGA, GTEx, and TARGET datasets.
View Article and Find Full Text PDFContinual deep reinforcement learning with task-agnostic policy distillation.
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December 2024
Department of Informatics, University of Hamburg, Hamburg, Germany.
Central to the development of universal learning systems is the ability to solve multiple tasks without retraining from scratch when new data arrives. This is crucial because each task requires significant training time. Addressing the problem of continual learning necessitates various methods due to the complexity of the problem space.
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