Background: The bulk metallic glass (BMG), Pd79Ag3.5P6Si9.5Ge2, has a high fracture toughness and has been found to accommodate post-yield stress, unlike most other BMG. Moreover, due to its greater noble gas composition it has a intrinsic corrosion resistance, ideal for dental and orthopedic implants.
Objective: This present study aimed to evaluate the in vivo application of Pd79Ag3.5P6Si9.5Ge2 in a large translational sheep model to assess its efficacy to be utilized as an endosteal device.
Methods: Twelve implants in the form of cylindrical rods (3 mm in diameter) were produced through rapid quenching. Each sheep (n = 12) received one osteotomy in the mandibular region using rotary instrumentation, which was filled with Pd79Ag3.5P6Si9.5Ge2. After 6- and 24-weeks the animals were euthanized, and samples collected en bloc to conduct histomorphometric analysis. The degree of osseointegration were assessed through bone-to-implant contact (BIC).
Results: All samples revealed favorable BIC along with with fibrous connective tissue layers at both 6- and 24-weeks. Bone along with interfacial remodeling was observed in proximity with the metallic glass surface at 6 weeks with higher degrees of bone organization being observed at the later healing time, 24 weeks.
Conclusions: The synthesized BMG, given its unique combination of toughness and strength, revealed potential to serve as an alternative to commonly used Ti alloys.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.3233/BME-221392 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A Versatile Dual-Responsive Shape-Memory Gripper via Additive Manufacturing Toward High-Performance Cross-Scale Objects Maneuvering.
Small
January 2025
Department of Materials Physics and New Energy Device School of Materials Science and Engineering, Hefei University of Technology, Hefei, 230009, China.
Smart grippers serving as soft robotics have garnered extensive attentions owing to their great potentials in medical, biomedical, and industrial fields. Though a diversity of grippers that account for manipulating the small objects (e.g.
View Article and Find Full Text PDFControllable Nano-Crystallization in Fluoroborosilicate Glass Ceramics for Broadband Visible Photoluminescence.
Nanomaterials (Basel)
January 2025
Sino-French Hoffmann Institute, School of Basic Medical Science, Guangzhou Medical University, Guangzhou 511436, China.
A transparent fluoroborosilicate glass ceramic was designed for the controllable precipitation of fluoride nanocrystals and to greatly enhance the photoluminescence of active ions. Through the introduction of BO into fluorosilicate glass, the melting temperature was decreased from 1400 to 1050 °C, and the abnormal crystallization in the fabrication process of fluorosilicate glass was avoided. More importantly, the controlled crystallizations of KZnF and KYbF in fluoroborosilicate glass ceramics enhanced the emission of Mn and Mn-Yb dimers by 6.
View Article and Find Full Text PDFReducing the Radioactive Surface Contamination Level of Cobalt-60-Contaminated Material with PVA-Glycerol-EDTA Combination Gel.
Gels
January 2025
Nuclear Chemical Engineering Study Program, Polytechnic Institute of Nuclear Technology-BRIN, Yogyakarta 55281, Central Java, Indonesia.
Decommissioning of nuclear facilities can be performed in stages. One of the stages and processes in decontamination is the decontamination process before dismantling or facility area recovery activities. Decontamination can be performed using various methods, primarily physical and chemical.
View Article and Find Full Text PDFBone Regeneration: Mini-Review and Appealing Perspectives.
Bioengineering (Basel)
January 2025
CIRIMAT, Toulouse INP, Université Toulouse 3 Paul Sabatier, CNRS, Université de Toulouse, 4 Allée Emile Monso, BP44362, CEDEX 4, 31030 Toulouse, France.
Bone is a natural mineral-organic nanocomposite protecting internal organs and allowing mobility. Through the ages, numerous strategies have been developed for repairing bone defects and fixing fractures. Several generations of bone repair biomaterials have been proposed, either based on metals, ceramics, glasses, or polymers, depending on the clinical need, the maturity of technologies, and knowledge of the natural constitution of the bone tissue to be repaired.
View Article and Find Full Text PDFDirect Synthesis of Hydrogen-Substituted Graphdiyne on Fluorine-Doped Tin Oxide Glass Substrates Using a Cu Sandwich Technique.
Langmuir
January 2025
Surface Science Laboratory, Graduate School of Engineering, Toyota Technological Institute, 2-12-1, Hisakata, Tempaku, Nagoya, Aichi 468-8511, Japan.
Hydrogen-substituted graphdiyne (HsGDY) is a two-dimensional material with an sp-sp carbon skeleton featuring a band gap and a porous structure that enhances ion diffusion. In previous reports, HsGDY growth was limited to metal substrates such as Cu, which then required transfer. Here, we developed a sandwich method that allows HsGDY to be grown directly on the target substrate.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!