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Positive feedback regulation between RpoS and BosR in the Lyme disease pathogen.
mBio
January 2025
Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
In , the causative agent of Lyme disease, differential gene expression is primarily governed by the alternative sigma factor RpoS (σ). Understanding the regulation of RpoS is crucial for elucidating how is maintained throughout its enzootic cycle. Our recent studies have shown that the homolog of Fur/PerR repressor/activator BosR functions as an RNA-binding protein that controls the mRNA stability.
View Article and Find Full Text PDFVesicoureteral Reflux in Children with Accidental Diagnosis of Unilateral Small Size Kidney.
Urol Res Pract
January 2025
Non-Communicable Pediatric Diseases Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, I.R. Iran.
Objective: A majority of small size kidney in children were diagnosed after a urinary tract infection (UTI) and with high-grade vesicoureteral reflux (VUR). This study was conducted in children who were diagnosed accidentally and investigated for VUR and UTI.
Methods: This longitudinal retrospective study was conducted in children with a diagnosis of a small kidney accidentally discovered by ultrasonography and referred to Children's Hospital in Babol, Iran, between 2012-2022.
Prevalence and Etiology of Maxillary Midline Diastema among University Students, Hodeidah Governorate, Yemen: A Cross-sectional Study.
J Contemp Dent Pract
October 2024
Department of Prosthetic Dental Science, College of Dentistry, Jazan University, Jazan, Saudi Arabia, Phone: +00966550599553, e-mail: Orcid: https://orcid.org/0000-0002-9623-261X.
Aim: This study assessed the prevalence and etiological factors of maxillary midline diastema (MMD) in students attending different colleges and universities in Al-Hodeidah governorate, Yemen.
Participants And Methods: A total of 1,661 participants from different universities in Al-Hodeidah governorate were assessed, analyzed, and screened for the presence or absence of MMD. Only 246 had positive MMD and were divided five age-groups.
Lesion Location and Possible Etiology of Acute Unilateral Vestibulopathy.
Int J Gen Med
January 2025
Department of Neurology, Aerospace Center Hospital, Peking University Aerospace School of Clinical Medicine, Beijing, 100049, People's Republic of China.
Objective: Acute unilateral vestibulopathy (AUVP) is quite common in clinical practice, but lesion localization and etiological diagnosis of AUVP remain the current clinical challenges, and have always been the focus for researchers. The study aimed to explore the lesion site and possible etiology of AUVP.
Methods: This study is a retrospective study.
Integrated transcriptomic analysis reveals dysregulated immune infiltration and pro-inflammatory cytokines in the secretory endometrium of recurrent implantation failure patients.
Life Med
October 2024
State Key Laboratory of Female Fertility Promotion, Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing 100191, China.
Recurrent implantation failure (RIF) is a leading impediment to assisted reproductive technology, yet the underlying pathogenesis of RIF remains elusive. Recent studies have sought to uncover novel biomarkers and etiological factors of RIF by profiling transcriptomes of endometrial samples. Nonetheless, the inherent heterogeneity among published studies and a scarcity of experimental validations hinder the identification of robust markers of RIF.
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