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Journey to diagnosis: An unfinished exploration of IgG4-related sclerosing cholangitis.
World J Clin Cases
November 2024
Department of Infectious Diseases, Affiliated Hospital of Zunyi Medical University, Zunyi 563000, Guizhou Province, China.
IgG4-related sclerosing cholangitis (IgG4-SC) is an inflammatory disease that leads to bile duct stricture, characterized by the infiltration of IgG4-positive plasma cells into the bile duct wall, thickening of the bile duct wall, and narrowing of the lumen. The differential diagnosis of IgG4-SC mainly includes primary sclerosing cholangitis, cholangiocarcinoma, and pancreatic cancer. IgG4-SC is often associated with autoimmune pancreatitis and can be accurately diagnosed based on clinical diagnostic criteria.
View Article and Find Full Text PDFIsolated IgG4-associated autoimmune hepatitis or the first manifestation of IgG4-related disease?
Hepatobiliary Pancreat Dis Int
August 2023
Department of Gastroenterology and Hepatology, Alfred Health, Melbourne 3004, VIC, Australia; Central Clinical School, Monash University, Melbourne 3004, VIC, Australia.
Isolated Liver Hilar Infiltration by IgG4 Inflammation Mimicking Cholangiocarcinoma.
Case Rep Gastroenterol
October 2016
Geneva University Hospitals, Geneva, Switzerland.
IgG4-related disease represents a heterogeneous group of disease characterized by infiltration of various tissues by IgG4 plasmocytes. In case of liver infiltration, this condition classically mimics primary sclerosing cholangitis or multifocal cholangiocarcinoma due to inflammation that preferentially affects the intra- and extrahepatic bile duct. Diagnostic criteria have recently been reviewed in order to better define the disease and help physicians make the diagnosis.
View Article and Find Full Text PDFIgG4-associated sclerosing cholangitis masquerading as hilar cholangiocarcinoma.
Indian J Gastroenterol
July 2016
Department of Surgical Oncology, Lilavati Hospital and Research Centre, A-791, Bandra Reclamation, Bandra West, Mumbai, 400 050, India.
IgG4-sclerosing cholangitis (IgG4-SC) commonly presents with type 1 autoimmune pancreatitis. Isolated IgG4-SC is rare. Differentiating IgG4-SC from cholangiocarcinoma preoperatively is challenging due to overlapping radio-clinical manifestations and difficult preoperative histology.
View Article and Find Full Text PDFPseudotumour formation in atheromatous coronary arteries.
J Forensic Leg Med
May 2015
Department of Histopathology, The National Heart and Lung Institute at the Royal Brompton Hospital, London, UK. Electronic address:
Three cases with mass like lesions (pseudotumours) surrounding atheromatous coronary arteries were referred to the Royal Brompton Hospital for expert pathology review. All were males with mean age 74 years (range 55-91). In all cases, coronial autopsies were carried out for sudden deaths in the community.
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