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Short-acting growth hormone supplementation for bone age and growth rate in children with idiopathic short stature: a meta-analysis.
BMC Pediatr
January 2025
Department of Child Health, West China Second University Hospital, Sichuan University, No.20, Section 3, Renmin South Road, Wuhou District, Chengdu City, 610041, Sichuan Province, China.
Objective: To explore the effect of short-acting growth hormone (GH) supplementation on bone age and growth rate of children with idiopathic short stature.
Methods: The authoritative databases such as PubMed, Medline, and Web of Science were extensively searched through the systematic and comprehensive literature retrieval strategy to compile the clinical research data on the treatment of idiopathic short stature with short-acting GH. The study will be strictly screened to ensure that all enrolled research subjects are patients with idiopathic short stature, and the intervention method is defined as short-acting GH replacement therapy, and a reasonable control group is set, such as placebo treatment, to ensure the scientificity and comparability of research results.
Effectiveness of tobacco advertising, promotion and sponsorship bans on smoking prevalence, initiation and cessation: a systematic review and meta-analysis.
Tob Control
January 2025
Griffith University School of Medicine and Dentistry, Gold Coast, Queensland, Australia.
Background: Bans on tobacco advertising, promotion and sponsorship (TAPS) have the potential to influence smoking behaviour. However, many countries are yet to implement such strategies.
Objective: This study aimed to synthesise contemporary evidence on the effectiveness of TAPS bans on smoking prevalence, initiation and cessation.
The Optimal Dosage and Duration of Omega-3 Polyunsaturated Fatty Acid Supplementation in Heart Failure Management: Evidence from a Network Meta-Analysis.
Adv Nutr
January 2025
Department of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK; Department of Psychiatry & Mind-Body Interface Laboratory (MBI-Lab), China Medical University Hospital, Taichung, Taiwan; College of Medicine, China Medical University, Taichung, Taiwan; An-Nan Hospital, China Medical University, Tainan, Taiwan. Electronic address:
Heart failure is a progressive condition associated with a high mortality rate. Despite advancements in treatment, many patients continue to experience less-than-ideal outcomes. Omega-3 polyunsaturated fatty acids (n-3 PUFAs) have been studied as a potential supplementary therapy for heart failure, but the optimal dosage and duration of supplementation remain unclear.
View Article and Find Full Text PDFTHE RELEVANCE OF THE EVOLUTIONARY APPROACH FOR UNDERSTANDING HEALTH AND DISEASE OF THE HUMAN BODY AND MIND.
Neurosci Biobehav Rev
January 2025
Department of Medicine and Surgery, Unit of Neuroscience, University of Parma, viale delle Scienze 11A, 43124 Parma (Italy). Electronic address:
Ultimate and proximate levels of analysis offer synergistic explanations can improve the search for causes of disease and their cures. Here we review how several principles of evolutionary biology such as historical contingencies, mismatches, trade-offs, sexual selection and genomic conflict are applied to problems in medicine and psychiatry. The application of evolutionary principles to many other domains of medicine, among them mental disorders, have not received the same reception from preclinical and clinical researchers.
View Article and Find Full Text PDFBackground: Anakinra is an interleukin-1 receptor antagonist (IL-1Ra). Since IL-1 has been shown to play a key role in the etiology of different autoinflammatory diseases, blocking its pathway has become an important therapeutic target, even in neonates.
Aims: We aimed to report our experience in using anakinra to treat specific neonatal inflammatory conditions.
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