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Early markers of baked milk and egg tolerance in young children with IgE-mediated immediate reactions.
Eur Ann Allergy Clin Immunol
January 2025
Division of Allergy and Immunology, Department of Pediatrics, Marmara University, School of Medicine, Istanbul, Turkey.
Children with milk and egg allergies have outcomes in which, three-quarters are tolerant to baked forms of the allergenic food. Identifying predictors of tolerance to baked foods for IgE-mediated immediate-type reactions may guide the early introduction of baked allergens to diet and tolerance development. This study explores factors associated with early tolerance to baked foods.
View Article and Find Full Text PDFMilk ladder: Who? When? How? Where? with the lowest risk of reaction.
Front Allergy
December 2024
Division of Pediatric Allergy, Koc University School of Medicine, Istanbul, Türkiye.
The milk ladder (ML) approach, which is the gradual reintroduction of the milk allergen from the least allergenic forms to the most allergenic forms into the diet of the patients, has been utilized mostly in non-IgE-mediated but in some countries also in IgE-mediated-CMPA due to its possible benefits which include nutrition, quality of life and tolerance induction. Despite increasing interest, so far, there is no guideline on ML; thus, the use of this approach shows discrepancies among healthcare professionals as many factors such as dietary habits, patient history, test results, workload, and facilities of the hospitals, the anxiety of the parents/patients may affect the decision on how, when, where and whom to use ML. Here, we reviewed current data on implementing the ML, suggested a 4-step ML including receipts and amounts, and shared our experience on optimal patient selection, appropriate time and steps for initiating ML, and time intervals between the steps targeting the lowest risk of reaction.
View Article and Find Full Text PDFThe evolution of nutritional care in children with food allergies - With a focus on cow's milk allergy.
J Hum Nutr Diet
February 2025
Section of Allergy and Immunology, University of Colorado/Children's Hospital Colorado, Boulder, Colorado, USA.
Cow's milk allergy (CMA) remains one of the most common and complex paediatric food allergies. In the last decade, our understanding has advanced in terms of immunoglobulin E (IgE)-mediated CMA and focus is now also paid to non-IgE-mediated CMA, particularly in some Western countries where incidence rates are high. We have had significant progress in the last 10 years in relation to our understanding of existing supportive tests for IgE-mediated CMA, with the advancement of newer tests, such as the basophil activation test (BAT), which have shown great promise.
View Article and Find Full Text PDFAAAAI-EAACI PRACTALL: Standardizing oral food challenges-2024 Update.
Pediatr Allergy Immunol
November 2024
Pediatric Allergy Unit, University Hospitals of Geneva, Geneva, Switzerland.
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Exploring Calcium Alginate-Based Gels for Encapsulation of to Enhance Stability in Functional Breadmaking.
Gels
October 2024
Department of Food Science and Technolgy, Faculty of Chemical Technology, Kaunas University of Technology, 50254 Kaunas, Lithuania.
This study focuses on evaluating the efficiency of acid-tolerant bacteria encapsulated in an alginate-based gel matrix during repeated sourdough fermentation cycles, as well as their preservation during storage and throughout baking at high temperature. A double-coating procedure was applied, involving the encapsulation of bacterial cells in calcium alginate, which was further coated with chitosan. The encapsulation efficiency (EE) did not show significant difference between alginate and alginate-chitosan (97.
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