Obstructed total anomalous pulmonary venous connection (TAPVC) represents a true pediatric cardiac emergency. The patient may present in extremis secondary to severe pulmonary hypertension and cardiogenic shock which increases perioperative mortality. We present a neonate who underwent a successful staged hybrid approach for an Infradiaphragmatic obstructed TAPVC.
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http://dx.doi.org/10.1111/jocs.17053 | DOI Listing |
J Plant Physiol
December 2024
College of Landscape Architecture and Art, Henan Agricultural University, 450002, Zhengzhou, China. Electronic address:
Sucrose is an essential energy substance for tree peony (Paeonia Suffruticosa) floral organ development. However, little is known about the sucrose regulatory network in tree peony. In this study, the promoter sequence of the tree peony sucrose transporter gene PsSUT2 was cloned.
View Article and Find Full Text PDFMol Biol (Mosk)
December 2024
Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991 Russia.
ENY2 is an evolutionarily conserved multifunctional protein and is a member of several complexes that regulate various stages of gene expression. ENY2 is a subunit of the TREX-2 complex, which is necessary for the export of bulk mRNA from the nucleus to the cytoplasm through the nuclear pores in many eukaryotes. The wide range of ENY2 functions suggests that it can also associate with other protein factors or complexes.
View Article and Find Full Text PDFAnal Chem
December 2024
Department of Clinical Laboratory Medicine, Southwest Hospital, Third Military Medical University (Army Medical University), 30 Gaotanyan, Shapingba DistrictChongqing 400038, China.
CRISPR/Cas12a-based diagnostics have great potential for sensing nucleic acids, but their application is limited by the sequence-dependent property. A platform termed miR-Cabiner (a universal NA sensing platform based on self-stacking scaded cyclic DA circuit-mdiated CISPR/Cas12a) is demonstrated herein that is sensitive and universal for analyzing miRNAs. This platform combines catalytic hairpin assembly (CHA) and hybrid chain reaction (HCR) into a unified circuit and finally cascades to CRISPR/Cas12a.
View Article and Find Full Text PDFSci Rep
December 2024
Research Center, Future University in Egypt, New Cairo, 11835, Egypt.
Image processing and pattern recognition methods have recently been extensively implemented in histopathological images (HIs). These computer-aided techniques are aimed at detecting the attentive biological markers for assisting the final cancer grading. Mitotic count (MC) is a significant cancer detection and grading parameter.
View Article and Find Full Text PDFACS Biomater Sci Eng
December 2024
Department of Bioengineering, University of Washington, Seattle, Washington 98195, United States.
Transplantable engineered organs could one day be used to treat patients suffering from end-stage organ failure. Yet, producing hierarchical vascular networks that sustain the viability and function of cells within human-scale organs remains a major challenge. Sacrificial templating has emerged as a promising biofabrication method that could overcome this challenge.
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