Thermodynamic database supports deciphering protein-nucleic acid interactions.

Trends Biotechnol

Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, Wuhan 430079, China. Electronic address:

Published: February 2023

The thermodynamics of protein-nucleic acid interactions (PNIs) is crucial for elucidating the mechanisms of molecular recognition and pathological consequences. The Protein-Nucleic Acid Thermodynamics Database (PNATDB) is a database containing experimentally determined thermodynamic parameters along with sequence, structural, and function data, which is available free online.

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http://dx.doi.org/10.1016/j.tibtech.2022.09.018DOI Listing

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