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Development of HRP-assisted rGO-FET biosensors for high-precision measurement of serological steroid hormones.
Anal Chim Acta
January 2025
Department of Medical Biotechnology, College of Life Science and Biotechnology, Dongguk University, Seoul, 04620, Republic of Korea. Electronic address:
Background: Sarcopenia, which is associated with many pathways and molecular mechanisms, not only deteriorates the quality of life in old age but is also linked to various diseases. The ratio between cortisol and dehydroepiandrosterone sulfate (DHEAS) was utilized as a candidate method to diagnose sarcopenia. The hormones can fluctuate in concentration throughout the day, so monitoring the ratio between the two hormones is necessary.
View Article and Find Full Text PDFMosaicism and intronic variants in RB1 gene revealed by next generation sequencing in a cohort of Spanish retinoblastoma patients.
Exp Eye Res
January 2025
Genetic Diagnosis Unit, Institute for Rare Diseases Research (IIER), Carlos III Institute of Health (ISCIII), Madrid, Spain; Center for Biomedical Research on Rare Diseases Network, Carlos III Institute of Health (ISCIII), Madrid, Spain (U758; CB06/07/1009; CIBERER-ISCIII).
Constitutional variants in the RB1 gene predispose individuals to the development of Retinoblastoma (RB) and the occurrence of second tumors in adulthood. Detection of causal RB1 gene variants is essential to establish the genetic diagnosis and to performing familial studies and counseling. In our cohort of 579 Spanish RB patients, 15% of cases suspected to have a genetic origin remained negative after traditional Sanger sequencing and Multiplex Ligation-dependent Probe Amplification (MLPA) of RB1 gene, likely due to the possibility of mosaicism or non-coding variants.
View Article and Find Full Text PDFSynthesis of zinc oxide/bismuth oxide nanocomposite photocatalyst for visible light-assisted degradation of synthetic dyes and antibacterial application.
Environ Sci Pollut Res Int
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School of Applied Sciences, Centurion University of Technology and Management, Bhubaneswar, Odisha, India.
Contamination of water resources by artificial coloring agents and the increasing incidence of bacterial illnesses are two significant environmental and public health issues that are getting worse day by day. Traditional treatment techniques frequently fail to address these problems adequately in a sustainable and environmental friendly way. In response, our study presents a novel photocatalyst that demonstrates superior photodegradation capability and antibacterial qualities in catering the above issues.
View Article and Find Full Text PDFSegregation of Constitutional Isomers of Some Aromatic Amines Exploiting the Changes of Photo-Luminescence Behaviour of Isoreticular Metal-Organic Frameworks.
Chem Asian J
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Jadavpur University, Department of Chemistry, INDIA.
Three different two dimensional Cd(II)-based metal-organic frameworks (MOFs) have been synthesized by utilizing same N,N'-donor ligand and three different functionalized dicarboxylate linkers namely isophthalate, 5-nitroisophthalate and 5-hydroxyisophthalate for compound 1, 2 and 3 respectively. The compounds that are isoreticular bi-walled 2D frameworks, show dual fluorescence emission spectra for their π-π* and n-π* excitation. Compound 1 is consists of unsubstituted bridging isophthalate whereas 2 and 3 are made with bridging isophthalate that are substituted by electron withdrawing -NO2 group and electron donating -OH group respectively.
View Article and Find Full Text PDFSimulations of Overhead Irrigation in a Greenhouse Setting Reveal the Potential for Splash Dispersal of Microconidia.
Plant Dis
December 2024
University of Florida Institute of Food and Agricultural Sciences, Plant Pathology, 2550 Hull Rd., Rm. # 1441 Fifield Hall, Gainesville, Florida, United States, 32611-0680;
Management of Fusarium wilt of Watermelon, caused by the fungus f. sp. , or Fon, requires pathogen monitoring in watermelon production systems.
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