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Mendelian randomization analysis reveals causal effects of migraine and its subtypes on early-onset ischemic stroke risk.
Sci Rep
December 2024
Department of Neurology, The First Affiliated Hospital of Zhengzhou University, JianShe Road 1#, Zhengzhou, 450000, China.
Previous observational studies have suggested at a potential link between migraine, particularly migraine with aura, and the susceptibility to early-onset ischemic stroke. We aimed to investigate the causal effects of genetically determined migraine and its subtypes on the risk of early-onset ischemic stroke using the two-sample Mendelian randomization method. Genetic instrumental variables associated with migraine and its subtypes were acquired from two sources with the largest sample sizes available.
View Article and Find Full Text PDF[The relationship of diet and nutrition with the frequency of migraine attacks].
Zh Nevrol Psikhiatr Im S S Korsakova
December 2024
Research Center of Neurology, Moscow, Russia.
Objective: To evaluate the relationship of diet and food components with the frequency of migraine attacks.
Material And Methods: Sixty patients (mean age 35.5±8.
Global and regional trends and projections of chronic pain from 1990 to 2035: Analyses based on global burden of diseases study 2019.
Br J Pain
December 2024
Department of Anesthesiology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.
Background: Chronic pain poses a significant public health challenge. We present the global and regional data on Prevalence, Incidence and Years Lived with Disability (YLDs) for Chronic pain from the Global burden of disease (GBD) study 2019 data and analyze their associations with Socio-demographic index (SDI), age, and gender, and the future trends from 2020 to 2035.
Methods: Regional trends in the burden of chronic pain and its association with age, gender, and SDI were assessed from 1990 to 2019.
Gestational Hypertension, Preeclampsia, and Eclampsia and Future Neurological Disorders.
JAMA Neurol
December 2024
Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden.
Importance: Gestational hypertension, preeclampsia, and eclampsia are established risk factors for stroke and dementia later in life. Whether these pregnancy complications are associated with an increased risk of new-onset neurological disorders within months to years after giving birth is not known.
Objective: To explore whether gestational hypertension, preeclampsia, and eclampsia are associated with new-onset migraine, headache, epilepsy, sleep disorder, or mental fatigue within months to years after giving birth.
Seasonal Variations in Triptan Prescription in Japan: A Nationwide Time-Series Analysis.
Brain Behav
December 2024
Department of Medical Affairs, Otsuka Pharmaceutical Co. Ltd, Tokyo, Japan.
Objective: This study aimed to investigate seasonal differences in migraine onset in Japan and associated trends in the prescription of triptan.
Background: The relationship between seasonal changes and the onset of migraine remains largely unknown.
Methods: We combined the large-scale medical claims data in Japan with city-level meteorological data presented by the Japan Weather Association.
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