We present a study case where the theory of sampling (TOS) is used to make defensible inferences in a nuclear forensic investigation. The forensic investigations focused on five suspicious radioactive materials seized in 2019. All errors introduced by sampling and sub-sampling the radioactive materials are evaluated according to TOS. A maximum sampling error of 35% was tolerated. The uses of TOS enabled the forensic team to make inferences about the seized materials and therefore make confidence-based statements about the exceeding of limits established in the Swiss Radiological Protection Ordinance for radioactive substances. The analysis of the isotope and activity ratios allowed the team to exclude some potential sources of the radioactive contamination; however, it was not possible to determine its origin precisely.
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http://dx.doi.org/10.1016/j.apradiso.2022.110513 | DOI Listing |
J Fam Psychol
January 2025
Department of Human Development and Family Science, Purdue University.
Theory and research suggest that racial discrimination is associated with attachment insecurity (Stern et al., 2022), whereas racial socialization is an integral aspect to fostering secure attachment with parents (Coard, 2022; Dunbar, Lozada, et al., 2022).
View Article and Find Full Text PDFPsychol Aging
January 2025
Department of Psychology, University of Trier.
Human cognitive abilities exhibit positive interrelationships that can be represented by a latent general intelligence factor (g). Differentiation hypotheses propose that there are systematic interindividual differences in the strength of g, specifically along the dimensions of ability level (ability differentiation) and age (age differentiation). Despite the potential implications for cognitive theory and assessment, the available evidence on the matter is inconclusive.
View Article and Find Full Text PDFJ Pers Soc Psychol
January 2025
Department of Psychology, University of Oslo.
The role of childhood activity level in personality development is still poorly understood. Using data from a prospective study following 939 children from age 1.5 to 16.
View Article and Find Full Text PDFJ Chem Theory Comput
January 2025
Computational Chemistry and Molecular Biophysics Section, Molecular Targets and Medications Discovery Branch, National Institute on Drug Abuse - Intramural Research Program, National Institutes of Health, Baltimore, Maryland 21224, United States.
We have developed a method that uses energy landscapes of unbound and bound ligands to compute reorganization free energies for end-point binding free-energy calculations. The method is applied to our previous simulations of fentanyl derivatives bound to the μ opioid receptor in different orientations. Whereas the mean interaction energy provides an ambiguous ranking of binding poses, interaction entropy and ligand reorganization strongly penalize geometric decoys such that native poses observed in CryoEM structures are best ranked.
View Article and Find Full Text PDFJ Chem Theory Comput
January 2025
Department of Biology, Chemistry and Pharmacy, Freie Universität Berlin, Arnimallee 22, 14195 Berlin, Germany.
This paper presents a grid-based approach to model molecular association processes as an alternative to sampling-based Markov models. Our method discretizes the six-dimensional space of relative translation and orientation into grid cells. By discretizing the Fokker-Planck operator governing the system dynamics via the square-root approximation, we derive analytical expressions for the transition rate constants between grid cells.
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