Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9817906 | PMC |
| http://dx.doi.org/10.1165/rcmb.2022-0386ED | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The neurobiology of thirst and salt appetite.
Neuron
December 2024
Department of Physiology, University of California, San Francisco, San Francisco, CA 94158, USA; Kavli Center for Fundamental Neuroscience, University of California, San Francisco, San Francisco, CA 94158, USA; Neuroscience Graduate Program, University of California, San Francisco, San Francisco, CA 94158, USA; Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA 94158, USA. Electronic address:
Article Synopsis
- The first act of life involved capturing water within cell membranes, making fluid balance vital for survival.
- The review explores how neural mechanisms compel animals to seek and consume water and salt, detailing how the brain processes information about blood osmolality and volume to trigger thirst and salt cravings.
- It also points out gaps in current knowledge about fluid homeostasis, including the identities of sensors that detect fluid imbalances and how drinking is regulated even when there’s no physiological need, like during meals.
Does the kidney influence the hunger for salt?
Kidney Int
December 2024
Edinburgh Kidney Research Group, The Centre for Cardiovascular Science, The University of Edinburgh, Scotland, UK. Electronic address:
Sympathetic overactivation contributes to hypertension. Renal denervation can reduce blood pressure. In the deoxycorticosterone acetate (DOCA)-salt model of hypertension, salt consumption contributes to high blood pressure.
View Article and Find Full Text PDFAldosterone-induced salt appetite requires HSD2 neurons.
JCI Insight
December 2024
Department of Neurology.
Article Synopsis
- Excessive production of aldosterone is linked to serious health risks, including heart disease, stroke, dementia, and increased mortality, primarily by promoting sodium retention and consumption.
- Researchers identified specific neurons in the human brain that are sensitive to aldosterone and express a genetic regulator called HSD2, which play a crucial role in salt intake.
- Experimental studies in mice confirmed that these HSD2 neurons are essential for aldosterone-induced salt consumption, suggesting they could be a potential target for treatments aimed at controlling dietary sodium intake.
Deciphering Spectroscopic Signatures of Competing Ca - Peptide Interactions.
J Phys Chem B
October 2024
Department of Molecular Spectroscopy, Max Planck Insitute for Polymer Research, Ackermannweg 10, Mainz 55128, Germany.
Calcium-protein interactions are of paramount importance in biochemistry. They are a key element in a number of biological processes, such as neuronal signaling. Therefore, an understanding of the interaction at the molecular level is highly desirable.
View Article and Find Full Text PDFGreater lactate accumulation does not alter peripheral concentrations of key appetite-regulating neuropeptides.
J Appl Physiol (1985)
November 2024
Department of Kinesiology and Physical Education, Wilfrid Laurier University, Waterloo, Ontario, Canada.
The potential mechanisms involved in lactate's role in exercise-induced appetite suppression require further examination. We used sodium bicarbonate (NaHCO) supplementation in a double-blind, placebo-controlled, randomized crossover design to explore lactate's role on neuropeptide Y (NPY), agouti-related peptide (AgRP), and alpha-melanocyte-stimulating hormone (α-MSH) concentrations. Twelve adults (7 males; 24.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!