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Pattern of skin sensitivity to various aeroallergens by skin prick test in patients of allergic airway disease in South Western Maharashtra. | LitMetric

AI Article Synopsis

  • - The study focused on identifying common aeroallergens causing allergic diseases like asthma and rhinitis in a specific region of India using skin prick testing (SPT).
  • - A total of 330 patients with diagnosed allergic airway diseases participated, and results showed that 82.27% had positive reactions to one or more allergens, with dust mites being the most prevalent.
  • - The findings highlight the need for increased awareness and targeted management of allergy issues in this area, given the significant prevalence of allergen sensitivity.

Article Abstract

Background: The prevalence of allergic diseases such as asthma and allergic rhinitis is high in the general population, and aeroallergens are the most common allergens that cause airway inflammation. Skin prick testing (SPT) is a validated method to diagnose IgE-mediated allergic diseases. The knowledge of allergen sensitivity pattern in this part of India is limited. The present study was undertaken to identify common aeroallergens prevalent in this area using a standardized SPT.

Methods: We did a cross-sectional hospital-based study. A total of 330 patients of proven allergic airway disease underwent SPT. We used a validated skin prick test which included 22 allergen extracts, 1 positive control, and 1 negative control.

Results: A total of 327 patients were included in the study. Two hundred seventy-one (82.27%, n = 327) patients had a positive SPT to one or more aeroallergen extract. The sensitivity of (49.85%) was seen in the maximum number of people followed by (47.70%).

Conclusions: In our study, dust mites were the most common aeroallergen seen in maximum study subjects.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9577266PMC
http://dx.doi.org/10.1016/j.mjafi.2020.06.011DOI Listing

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