Background: Fully porous acetabular shells are an appealing choice for patients with extensive acetabular defects undergoing revision total hip arthroplasty (rTHA). This study reports on the early outcomes of a novel 3-D printed fully porous titanium acetabular shell in revision acetabular reconstruction.
Methods: A multicenter retrospective study of patients who received a fully porous titanium acetabular shell for rTHA with a minimum of 2 years of follow-up was conducted. The primary outcome was rate of acetabular revision.
Results: The final study cohort comprised 68 patients with a mean age of 67.6 years (standard deviation 10.4) and body mass index of 29.5 kg/m (standard deviation 5.9). Ninety-four percent had a preoperative Paprosky defect grade of 2A or higher. The average follow-up duration was 3.0 years (range 2.0-5.1). Revision-free survivorship at 2 years was 81% for all causes, 88% for acetabular revisions, and 90% for acetabular revision for aseptic acetabular shell failure. Eight shells were explanted within 2 years (12%): 3 for failure of osseointegration/aseptic loosening (4%) after 15, 17, and 20 months; 3 for infection (4%) after 1, 3, and 6 months; and 2 for instability (3%). At the latest postoperative follow-up, all unrevised shells showed radiographic signs of osseointegration, and none had migrated.
Conclusions: This novel 3-D printed fully porous titanium shell in rTHA demonstrated good survivorship and osseointegration when used in complex acetabular reconstruction at a minimum of 2 years.
Level Of Evidence: IV, case series.
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http://dx.doi.org/10.1016/j.artd.2022.08.007 | DOI Listing |
Sci Rep
December 2024
Department of Mechanical Engineering, Qom University of Technology, Qom, 37195-1519, Iran.
This study investigates the use of multi-layered porous media (MLPM) to enhance thermal energy transfer within a counterflow double-pipe heat exchanger (DPHE). We conducted computational fluid dynamics (CFD) simulations on DPHEs featuring five distinct MLPM configurations, analyzed under both fully filled and partially filled conditions, alongside a conventional DPHE. The impact of various parameters such as porous layer arrangements, thickness, and flow Reynolds numbers on pressure drop, logarithmic mean temperature difference (LMTD), and performance evaluation criterion (PEC) was assessed.
View Article and Find Full Text PDFEur J Nucl Med Mol Imaging
December 2024
Department of Radiation Oncology, Stanford University, Stanford, CA, USA.
Purpose: Nanoparticles are highly efficient vectors for ferrying contrast agents across cell membranes, enabling ultra-sensitive in vivo tracking of single cells with positron emission tomography (PET). However, this approach must be fully characterized and understood before it can be reliably implemented for routine applications.
Methods: We developed a Langmuir adsorption model that accurately describes the process of labeling mesoporous silica nanoparticles (MSNP) with Ga.
Adv Mater
December 2024
School of Chemistry and Chemical Engineering, Northwestern Polytechnical University, Xi'an, Shaanxi, 710072, China.
Carbon-supported single-atom catalysts exhibit exceptional properties in acidic CO reduction. However, traditional carbon supports fall short in building high-site-utilization and CO-rich interfacial environments, and the structural evolution of single-atom metals and catalytic mechanisms under realistic conditions remain ambiguous. Herein, an interconnected mesoporous carbon nanofiber and carbon nanosheet network (IPCF@CS) is reported, derived from microphase-separated block copolymer, to improve catalytic efficiency of isolated Ni.
View Article and Find Full Text PDFJ Am Chem Soc
December 2024
Department of Chemistry, Graduate School of Science, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, Aichi 464-8602, Japan.
PtGd alloy nanoparticles supported in hollow mesoporous carbon spheres (HMCS; ) were successfully prepared by the thermal reduction of organometallic Pt and Gd complexes without oxygen atoms supported in the pores of HMCS. The structures of PtGd alloy nanoparticles were fully characterized by TEM, HAADF-STEM-EDS, XRD, XAFS, and XPS, suggesting the formation of uniform PtGd alloy nanoparticles with an average particle size of 5.9 nm.
View Article and Find Full Text PDFInorg Chem
December 2024
Key Lab of Organic Optoelectronics & Molecular Engineering of Ministry of Education, Department of Chemistry, Tsinghua University, No.30, Shuangqing Avenue, Beijing, Haidian 100084, China.
Cyclic compounds are appealing owing to their intrinsic porous structures and facile accessibility as building blocks (BBs) for fabricating high-order assemblies. Nevertheless, the modular synthesis of such molecular entities and their subsequent controlled assembly are still very challenging. Herein, we report the synthesis of a gigantic molybdenum blue (MB) wheel {Mo} (), featuring a skirt-shaped structure dimerized from {Mo}.
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