The pontobulbar body (PBB) is located in the cerebellopontine angle caudally to the cochlear nuclear complex (CN). We found the common boundary between these two structures on the surface of the brain stem as well as within it. We used the Kluver-Barrera staining technique to characterize different neuronal types adjacent to the boundary. Although the majority of them in the CN were globular, we also saw a substantial number of spherical neurons. Neurons in the PBB were substantially different in shape and were mainly angular. The boundary between the PBB and CN at their closest contact runs around the caudal side of the ventral cochlear nucleus and the most proximal part of the eighth nerve. In the more dorsal region, the PBB is completely separated from the CN by the brain stem tissue. In the ventral region, the PBB runs between the seventh and eighth nerves, and it is adjacent to both. These results might aid accurate placement of the central electroauditory prosthesis and further understanding of the general anatomy of the cerebellopontine angle.

Download full-text PDF

Source
http://dx.doi.org/10.1288/00005537-198709000-00001DOI Listing

Publication Analysis

Top Keywords

pontobulbar body
8
cerebellopontine angle
8
brain stem
8
region pbb
8
pbb
5
anatomical relationships
4
relationships cochlear
4
cochlear nuclei
4
nuclei pontobulbar
4
body significance
4

Similar Publications

Monitoring the effects of mobile phone use on the brain by proton magnetic resonance spectroscopy.

Int J Radiat Biol

September 2006

Département de Radiologie, Hôpital Saint-Luc du CHUM, Université de Montréal, Montreal, Quebec, Canada.

Purpose: To determine whether extensive use of mobile phones affects brain metabolites detectable by proton magnetic resonance spectroscopy (1H MRS).

Materials And Methods: Twenty-one extensive mobile phone users (average use = 5.5 +/- 2.

View Article and Find Full Text PDF

The pre-cerebellar nuclei act as a gate for the entire neocortical, brainstem and spinal cord afferent input destined for the cerebellum. Since no pathoanatomical studies of these nuclei had yet been performed in spinocerebellar ataxia type 2 (SCA2) or type 3 (SCA3), we carried out a detailed postmortem study of the pre-cerebellar nuclei in six SCA2 and seven SCA3 patients in order to further characterize the extent of brainstem degeneration in these ataxic disorders. By means of unconventionally thick serial sections through the brainstem stained for lipofuscin pigment and Nissl material, we could show that all of the pre-cerebellar nuclei (red, pontine, arcuate, prepositus hypoglossal, superior vestibular, lateral vestibular, medial vestibular, interstitial vestibular, spinal vestibular, vermiform, lateral reticular, external cuneate, subventricular, paramedian reticular, intercalate, interfascicular hypoglossal, and conterminal nuclei, pontobulbar body, reticulotegmental nucleus of the pons, inferior olive, and nucleus of Roller) are among the targets of both of the degenerative processes underlying SCA2 and SCA3.

View Article and Find Full Text PDF

Involvement of precerebellar nuclei in multiple system atrophy.

Neuropathol Appl Neurobiol

February 2003

Institute for Clinical Neuroanatomy, JW Goethe University, Frankfurt am Main, Germany.

In this semiquantitative study based on 26 post-mortem cases, we describe the involvement of precerebellar nuclei in multiple system atrophy (MSA), a progressive degenerative disorder of the human central nervous system characterized by abnormal, argyrophilic and alpha-synuclein immunopositive intracellular inclusions within selectively vulnerable oligodendrocytes and nerve cells. The Campbell-Switzer silver-pyridine technique with alpha-synuclein immunoreactions using 100-microm thick sections is recommended over more conventional methods, thereby permitting visualization of the pertinent lesions in greater detail and facilitating post-mortem diagnosis of MSA specimens. Affected oligodendrocytes occur in specific fibre tracts and grey matters, with most pathology being observed in projections from the precerebellar nuclei to the cerebellum (ponto-cerebellar, olivo-cerebellar, reticulo-cerebellar tracts) and in descending/ascending fibre tracts of the motor system (cortico-pontine, cortico-bulbar, cortico-spinal, spino-reticular, spino-olivary, spino-cerebellar tracts).

View Article and Find Full Text PDF

Involvement of precerebellar nuclei in Pick's disease.

Exp Neurol

October 1998

Department of Anatomy, Johann Wolfgang Goethe University, Theodor Stern Kai 7, Frankfurt/Main, D-60590, Germany.

Pick's disease is a progressive degenerative disorder of the human brain which involves not only numerous areas of the cerebral cortex but also a characteristic set of subcortical nuclei. The disorder is associated with the formation of abnormal and hyperphosphorylated tau protein, which occurs in only a few susceptible neuronal types and leads to major cytoskeletal alterations. Preferentially affected by the destructive process are small nerve cells of both cortical areas and subcortical nuclei.

View Article and Find Full Text PDF

[Recent data on the physiopathology of gaze].

Bull Acad Natl Med

May 1994

Laboratoire de Physiologie de la perception et de l'action, Collège de France, CNRS, Paris.

This paper presents a summary of results which concern the neuronal mechanisms underlying the control of gaze. The development of techniques of recording from alert animals and combining functional analysis of neuronal activity with intracellular marking by horse-radish peroxidase has allowed a study of the neuronal mechanisms underlying the vestibulo-ocular reflex and the generation of saccades. The results of these analysis show that there is a close interaction at the level of the brainstem between this two elements of the oculomotor repertoire.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!