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Meta-analysis of retinal transcriptome profiling studies in animal models of myopia.
Front Med (Lausanne)
January 2025
Department of Ophthalmology, Emory University, Atlanta, GA, United States.
Objective: Myopia prevalence is increasing at alarming rates, yet the underlying mechanistic causes are not understood. Several studies have employed experimental animal models of myopia and transcriptome profiling to identify genes and pathways contributing to myopia. In this study, we determined the retinal transcriptome changes in response to form deprivation in mouse retinas.
View Article and Find Full Text PDFBeta oscillations predict the envelope sharpness in a rhythmic beat sequence.
Sci Rep
January 2025
RITMO Centre for Interdisciplinary Studies in Rhythm, Time and Motion, University of Oslo, Forskningsveien 3A, Oslo, 0373, Norway.
Periodic sensory inputs entrain oscillatory brain activity, reflecting a neural mechanism that might be fundamental to temporal prediction and perception. Most environmental rhythms and patterns in human behavior, such as walking, dancing, and speech do not, however, display strict isochrony but are instead quasi-periodic. Research has shown that neural tracking of speech is driven by modulations of the amplitude envelope, especially via sharp acoustic edges, which serve as prominent temporal landmarks.
View Article and Find Full Text PDFStrength of Low-Frequency EEG Phase Entrainment to External Stimuli Is Associated with Fluctuations in the Brain's Internal State.
eNeuro
January 2025
Cognitive Psychology Unit, Faculty of Social Sciences, Leiden University, Leiden, Alaska 2333, The Netherlands.
The brain attends to environmental rhythms by aligning the phase of internal oscillations. However, the factors underlying fluctuations in the strength of this phase entrainment remain largely unknown. In the present study, we examined whether the strength of low-frequency electroencephalography (EEG) phase entrainment to rhythmic stimulus sequences varied with the pupil size and posterior alpha-band power, thought to reflect the arousal level and excitability of posterior cortical brain areas, respectively.
View Article and Find Full Text PDFInvestigating Neurometabolite Changes in Response to Median Nerve Stimulation.
Brain Behav
January 2025
School of Psychology, University of Nottingham University Park, Nottingham, UK.
Background: Rhythmic median nerve stimulation (MNS) at 10 Hz has been shown to cause a substantial reduction in tic frequency in individuals with Tourette syndrome. The mechanism of action is currently unknown but is hypothesized to involve entrainment of oscillations within the sensorimotor cortex.
Objective: We used functional magnetic resonance spectroscopy (fMRS) to explore the dynamic effects of MNS on neurometabolite concentrations.
Light-regulated microRNAs shape dynamic gene expression in the zebrafish circadian clock.
PLoS Genet
January 2025
School of Life Sciences, Gansu Key Laboratory of Biomonitoring and Bioremediation for Environmental Pollution, Lanzhou University, Lanzhou, China.
A key property of the circadian clock is that it is reset by light to remain synchronized with the day-night cycle. An attractive model to explore light input to the circadian clock in vertebrates is the zebrafish. Circadian clocks in zebrafish peripheral tissues and even zebrafish-derived cell lines are entrainable by direct light exposure thus providing unique insight into the function and evolution of light regulatory pathways.
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