Human knowledge models: Learning applied knowledge from the data.

PLoS One

Medical Analytics Group, Massachusetts General Hospital, Boston, Massachusetts, United States of America.

Published: October 2022

Artificial intelligence and machine learning have demonstrated remarkable results in science and applied work. However, present AI models, developed to be run on computers but used in human-driven applications, create a visible disconnect between AI forms of processing and human ways of discovering and using knowledge. In this work, we introduce a new concept of "Human Knowledge Models" (HKMs), designed to reproduce human computational abilities. Departing from a vast body of cognitive research, we formalized the definition of HKMs into a new form of machine learning. Then, by training the models with human processing capabilities, we learned human-like knowledge, that humans can not only understand, but also compute, modify, and apply. We used several datasets from different applied fields to demonstrate the advantages of HKMs, including their high predictive power and resistance to noise and overfitting. Our results proved that HKMs can efficiently mine knowledge directly from the data and can compete with complex AI models in explaining the main data patterns. As a result, our study reveals the great potential of HKMs, particularly in the decision-making applications where "black box" models cannot be accepted. Moreover, this improves our understanding of how well human decision-making, modeled by HKMs, can approach the ideal solutions in real-life problems.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9584406PMC
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0275814PLOS

Publication Analysis

Top Keywords

machine learning
8
hkms
6
human
5
models
5
knowledge
5
human knowledge
4
knowledge models
4
models learning
4
learning applied
4
applied knowledge
4

Similar Publications

Computational Methods for Predicting Chemical Reactivity of Covalent Compounds.

J Chem Inf Model

January 2025

Department of Medicinal Chemistry, School of Pharmacy, Fudan University, 826 Zhangheng Road, Shanghai 201203, People's Republic of China.

In recent decades, covalent inhibitors have emerged as a promising strategy for therapeutic development, leveraging their unique mechanism of forming covalent bonds with target proteins. This approach offers advantages such as prolonged drug efficacy, precise targeting, and the potential to overcome resistance. However, the inherent reactivity of covalent compounds presents significant challenges, leading to off-target effects and toxicities.

View Article and Find Full Text PDF

Bimodal In Situ Analyzer for Circular RNA in Extracellular Vesicles Combined with Machine Learning for Accurate Gastric Cancer Detection.

Adv Sci (Weinh)

January 2025

Department of Laboratory Medicine, Guangdong Provincial Key Laboratory of Precision Medical Diagnostics, Guangdong Engineering and Technology Research Center for Rapid Diagnostic Biosensors, Guangdong Provincial Key Laboratory of Single Cell Technology and Application, School of Laboratory Medicine and Biotechnology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, 510515, P. R. China.

Circular RNAs in extracellular vesicles (EV-circRNAs) are gaining recognition as potential biomarkers for the diagnosis of gastric cancer (GC). Most current research is focused on identifying new biomarkers and their functional significance in disease regulation. However, the practical application of EV-circRNAs in the early diagnosis of GC is yet to be thoroughly explored due to the low accuracy of EV-circRNAs analysis.

View Article and Find Full Text PDF

Bacterial Leaf Blight (BLB) usually attacks rice in the flowering stage and can cause yield losses of up to 50% in severely infected fields. The resulting yield losses severely impact farmers, necessitating compensation from the regulatory authorities. This study introduces a new pipeline specifically designed for detecting BLB in rice fields using unmanned aerial vehicle (UAV) imagery.

View Article and Find Full Text PDF

Purpose: In this study, we investigated the performance of deep learning (DL) models to differentiate between normal and glaucomatous visual fields (VFs) and classify glaucoma from early to the advanced stage to observe if the DL model can stage glaucoma as Mills criteria using only the pattern deviation (PD) plots. The DL model results were compared with a machine learning (ML) classifier trained on conventional VF parameters.

Methods: A total of 265 PD plots and 265 numerical datasets of Humphrey 24-2 VF images were collected from 119 normal and 146 glaucomatous eyes to train the DL models to classify the images into four groups: normal, early glaucoma, moderate glaucoma, and advanced glaucoma.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!