AI Article Synopsis
- The review examines trends and clinical characteristics of HIV and cerebrovascular disease in low-to-middle-income countries (LMICs) from 1990 to 2021, highlighting the emerging complexities of this health issue.
- Findings show that with the advent of antiretroviral therapy (ART), people living with HIV are aging and experiencing more cerebrovascular events, yet there's a notable lack of documentation on these events in LMICs.
- The study emphasizes the urgent need for more research and standardized reporting to improve understanding and intervention strategies for cerebrovascular disease in adults living with HIV in these regions.
Article Abstract
Purpose Of The Review: To describe trends and clinical characteristics of HIV and cerebrovascular disease between 1990 and 2021 in LMICs and identify the gaps in our understanding.
Recent Findings: In the era of antiretroviral therapy (ART), people living with HIV (PLWH) live longer and risk excess cerebrovascular events due to ageing and HIV-driven factors. Despite the highest burden of HIV infection in low-to-middle income countries, there is underreporting in the literature of cerebrovascular events in this population. We systematically reviewed published literature for primary clinical studies in adult PLWH and cerebrovascular disease in LMICs. The clinical phenotype of cerebrovascular disease among PLWH over the last three decades in LMICs has evolved and transitioned to an older group with overlapping cerebrovascular risk factors. There is an important need to increase research in this population and standardise reporting to facilitate understanding, guide development of appropriate interventions, and evaluate their impact.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9759508 | PMC |
| http://dx.doi.org/10.1007/s11904-022-00627-9 | DOI Listing |
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